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Minimally Invasive Radioguided Parathyroidectomy — MIRP  

Primary Hyperparathyroidism Clinical Trial

Official title:
Minimally Invasive Radioguided Parathyroidectomy

Clinical Trial Summary

The main purpose of this research study is to evaluate the effectiveness of a minimally invasive surgical approach to removing parathyroid gland(s). The researchers are also interested in analyzing abnormal parathyroid tissue for changes in genes and proteins that may contribute to overactive parathyroid gland(s).

Clinical Trial Description

The specific aims of this study are to determine the safety and efficacy of minimally invasive radioguided parathyroidectomy, to determine the positive and negative predictive value of sestamibi scanning to detect parathyroid adenomas, and to differentiate adenomas from parathyroid hyperplasia. In addition, this study aims to determine the value of intraoperative parathyroid hormone assay to verify biochemical cure of primary hyperparathyroidism, to determine whether minimally invasive radioguided parathyroidectomy is cos-effective, and to collect abnormal parathyroid tissue at the time of surgery for tissue analysis. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01530919
Study type Observational
Source University of Louisville
Contact
Status Completed
Phase N/A
Start date September 1998
Completion date April 2017
View Details
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