Primary Hypercholesterolemia Clinical Trial
Official title:
A Placebo Controlled, Double Blind, Randomised, 12-Week, Phase ii Study to Assess the Safety and Efficacy of KB2115 in Patients With Primary Hypercholesterolemia
Eprotirome (KB2115) is a liver selective thyroid hormone that can induce hyperthyroidism in
the liver, while an euthyroid state is preserved in the extrahepatic tissue. Eprotirome has
in a clinical 2-weeks studies demonstrated pronounced reduction of independent risk factors
for the development of atherosclerotic cardiovascular diseases.
The purpose of the study is to assess the efficacy and safety of KB2115 as monotherapy
following 12 weeks of exposure compared to placebo. The aim of the study is to assess
efficacy (LDL-cholesterol lowering effects) and safety of KB2115.
n/a
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double-Blind, Primary Purpose: Prevention
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