Primary Hyperaldosteronism Clinical Trial
Official title:
A Pilot, Single-blind, Forced-titration Study to Assess the Hemodynamic and Hormonal Effects, Safety and Tolerability of the Aldosterone Synthase Inhibitor LCI699 in Patients With Primary Hyperaldosteronism
The purpose of this study is to determine if LCI699, thorough reductions in aldosterone, can lower BP in patients with Primary hyperaldosteronism.
n/a
Allocation: Non-Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Single Blind (Subject), Primary Purpose: Treatment
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT01728493 -
Primary Aldosteronism in General Practice: Organ Damage, Epidemiology and Treatment
|
N/A | |
| Completed |
NCT02934399 -
Dynamic Hormone Diagnostics in Endocrine Disease
|
||
| Enrolling by invitation |
NCT03474237 -
A Prospective Cohort Study for Patients With Adrenal Diseases
|
||
| Completed |
NCT01978132 -
Primary Hyperaldosteronism and Ischemia-reperfusion Injury
|
N/A | |
| Completed |
NCT02938910 -
Study of Myocardial Interstitial Fibrosis in Hyperaldosteronism
|
N/A | |
| Recruiting |
NCT04278404 -
Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)
|
||
| Completed |
NCT01761344 -
Intraoperative Analysis of Cortisol During Adrenal Vein Sampling
|
N/A | |
| Recruiting |
NCT05636995 -
HyperAldosteronism in Pregnancy Predicted Impacts (H.A.P.P.I. Trial)
|
||
| Recruiting |
NCT04251780 -
Tissue K+ in Primary Hyperaldosteronism
|
N/A | |
| Completed |
NCT03405025 -
Radiofrequency Endoscopic Ablation With Ultrasound Guidance: a Non-surgical Treatment for Aldosterone-producing Adenomas
|
N/A | |
| Completed |
NCT01567111 -
11C-Metomidate PET Versus Adrenal Vein Sampling in Primary Aldosteronism
|
N/A |