Clinical Trials Logo

Clinical Trial Summary

Headache is one of the common causes of emergency department admissions and constitutes approximately 2%. Although the exact mechanism is not clear, It is known that high-flow oxygen therapy is effective in headache treatment. There are limited studies related to the use of oxygen therapy in headaches and its derivatives in the literature. In this study, the investigators aimed to compare the high and medium flow oxygen therapies with placebo in primary headache disorders.


Clinical Trial Description

Four different treatment methods were determined; 1) high-flow oxygen (15lt/min oxygen), 2) medium-flow oxygen (8lt/min oxygen), 3) high-flow room air as placebo (15 lt/min room air), 4) medium-flow room air as placebo (8 lt/min room air). All four treatment methods will be applied to all patients included in the study. One of the four treatments will be randomly applied at each separate ED admission with a gap of 1 week or more in between. This randomization will be performed by a computer at the time of admission. A study nurse will administer the patient's therapy according to the computer's current decision for 15 minutes. Patients and treating physicians will be blinded to the selected therapy. After 15 minutes of the end of treatment (at the 30th minute of the start of treatment), the treating physician will ask patients if they need rescue analgesia and analgesia will be administered if necessary. Additional analgesia is at the discretion of the treating physician. Patient data, including demographics, medical history, and findings of a physical examination performed before and after therapy will be recorded by the treating physician. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05511155
Study type Observational
Source Aksaray University Training and Research Hospital
Contact
Status Completed
Phase
Start date July 1, 2022
Completion date September 30, 2022

See also
  Status Clinical Trial Phase
Completed NCT00449787 - Comparing Naproxen to Sumatriptan for Emergency Headache Patients Phase 4
Recruiting NCT04080258 - Effectiveness of Osteopathic Manipulative Therapy in Paediatric Patients, With High Frequency Headache. N/A
Active, not recruiting NCT04178252 - Effectiveness of Eye Mask and Noise Reduction Headset in Primary Headache N/A
Not yet recruiting NCT05057533 - Primary Headaches and Irritable Bowel Syndrome.
Enrolling by invitation NCT05760625 - Gender Differences and Features of the Clinical Course of Primary Headaches
Withdrawn NCT05337930 - Feasibility of a Developmentally-tailored Mobile App for Tracking Mood and Pain in Children With Migraine N/A
Active, not recruiting NCT05023460 - Treatment of Chronic Cluster Headache With TENS and ONS N/A
Recruiting NCT03499392 - Primary Headache and Psychological Factors, Mental Functioning and Attachment Modalities. N/A