Iris Tissue in Primary Congenital Glaucoma

Primary Congenital Glaucoma Clinical Trial

Official title: Histopathological Examination of Iris Tissue in Primary Congenital Glaucoma

Status Not yet recruiting

Clinical Trial Summary

To present the histopathological features of the iris tissue in primary congenital glaucoma which may play a role in pathogenesis

Clinical Trial Description

Primary congenital glaucoma etiology still remains obscure . originally barkan , and later Worst , proposed that a membrane covered the anterior chamber angle and blocked aqueous outflow , but the presence of that membrane has not been established histopathologically to date . Now most authors believe that the site of obstruction is the trabecular meshwork rather than an overlying membrane . Maldevelopment of the anterior segment is present in all forms of congenital glaucoma . this maldevelopment may involve the trabecular meshwork alone or the trabecular meshwork in combination with the iris or cornea or both. In approcimately 50% of patients , isolated trabeculodysgensis is the only developmental ocular anomaly found .This is the classic defect found in primary congenital glaucoma .These eyes have no developmental anomalies of iris or cornea present except abnormal insertion of the iris into the angle ;

Related Conditions & MeSH terms

• Glaucoma
• Primary Congenital Glaucoma

• NCT number: NCT04079725
• Study type: Interventional
• Source: Assiut University
• Contact: Omar Abdelkarem Hasan, M.B.B.Ch.
• Phone: +201000525341
• Email: oabdelkarem@gmail.com
• Status: Not yet recruiting
• Phase: N/A
• Start date: December 2020
• Completion date: March 2022