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Diagnosis; Objective RespOnse; THErApy — DOROTHEA  

Primary CNS Lymphoma Clinical Trial

Official title:
Mutational Analysis in the Cerebrospinal Fluid to Improve Diagnostic Sensitivity, Response Definition and Precision Treatment in Primary Central Nervous System Lymphoma

Clinical Trial Summary

Thi is a prospective and low-intervention clinical trial. We propose to design a panel of "core" genetic alterations by sequencing Cerebral Spinal Fluid (CSF) DNA in patients with confirmed or suspicious Primary Central Neurvous System Lymphoma (PCNSL) with the aim to improve diagnostic sensitivity, response assessment and monitoring early CNS relapse in routine practice. Enrolled patients will receive conventional treatments according to well-established international guidelines, DNA assessments will not influence the treatment choices.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05036564
Study type Interventional
Source IRCCS San Raffaele
Contact Andrés J.M. Ferreri, MD
Phone 02 2643 7649
Email ferreri.andres@hsr.it
Status Recruiting
Phase N/A
Start date October 16, 2020
Completion date April 30, 2024
View Details
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