Clinical Trials Logo

Clinical Trial Summary

Despite medical advances, cancer remains the leading cause of death by disease in children. Brain tumors are the second most common cause of cancer in children after leukemia, representing 25% of pediatric cancers. The overall survival rate is about 50% with extremes ranging from less than 5% to more than 90% depending on the histological type of brain tumor. The end of life of children with a brain tumor is marked by the possibility of discomfort symptoms, painful or not, and by a progressive neurological deterioration, which makes the management of these children complex for both families and health professionals. Over the last decade, the concept of palliative care has been increasingly integrated into pediatric onco-hematology services with the primary objective of better symptom control in a global approach to the child and his or her family in order to aim at a better quality of life.


Clinical Trial Description

The main objective of the study is to compare the occurrence and management of end-of-life symptoms in children who died of a primary brain tumor over 2 periods, in 2009 - 2010 and in 2019 - 2020, followed in the Pediatric Oncology departments of Strasbourg, Besançon, Dijon, Nancy and Reims. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05660499
Study type Observational
Source University Hospital, Strasbourg, France
Contact Nadine COJEAN, MD
Phone 33 6 21 11 16 01
Email nadine.cojean@chru-strasbourg.fr
Status Recruiting
Phase
Start date February 15, 2021
Completion date December 31, 2023

See also
  Status Clinical Trial Phase
Recruiting NCT05539677 - Biobank and Register of Patients With Agresive Tumors for Translational and Analytical Research
Recruiting NCT04066465 - Neurocognitive Function After Proton Therapy in Children and Adolescents
Completed NCT02392078 - Laser Ablation of Abnormal Neurological Tissue Using Robotic NeuroBlate System
Not yet recruiting NCT02272452 - Assistance in Neurosurgery (ExtempoRMN) N/A
Recruiting NCT06104488 - A Study of Avutometinib for People With Solid Tumor Cancers Phase 1
Completed NCT02338037 - Neuropharmacokinetics of Eribulin Mesylate in Treating Patients With Primary or Metastatic Brain Tumors Early Phase 1
Completed NCT05328739 - The Effect of Home Care Planned According to Orem in Patients With Primary Brain Tumor and Their Caregivers N/A
Completed NCT02034708 - Efficacy Evaluation of Dotarem®-Enhanced MRI Compared to Gadovist®/Gadavist®-Enhanced MRI in the Diagnosis of Brain Tumors Phase 4
Terminated NCT00629395 - Computerized Cognitive Training for Childhood Cancer Survivors N/A
Completed NCT04919993 - CBT for Insomnia in Primary Brain Tumor Patients N/A
Completed NCT04075370 - Exploring Compensation to Maintain Cognitive Function in Adults Newly Diagnosed With Brain Cancer
Completed NCT01242566 - Temozolomide in Elderly Patients With KPS < 70 Phase 2
Recruiting NCT01535430 - Assessment of Eloquent Function in Brain Tumor Patients
Completed NCT00285324 - Diffusion Tensor MRI to Distinguish Brain Tumor Recurrence From Radiation Necrosis N/A
Recruiting NCT03684109 - Non-invasive Glioma Characterization Through Molecular Imaging N/A
Recruiting NCT05576103 - Longitudinal Prospective Study of Neurocognition & Neuroimaging in Primary BT Patients
Not yet recruiting NCT00265174 - Serum DNA Analysis: Potential Application for Diagnosis and Prognosis in Brain Cancer. N/A
Recruiting NCT05106296 - Chemo-immunotherapy Using Ibrutinib Plus Indoximod for Patients With Pediatric Brain Cancer Phase 1
Completed NCT04118426 - Cognitive Function After Radiation Therapy for Brain Tumours
Recruiting NCT02693405 - Executive and Socio-cognitive Functions in Survivors of Primary Brain Tumor: Impact on Patients' Quality of Life N/A