The Effect of Phacoemulsification on Intraocular Pressure in Primary Angle Closure Glaucoma (PACG) Patients At Phanat Nikhom Hospital, Chonburi Province

Primary Angle Closure Glaucoma Clinical Trial

Official title:

The Effect of Phacoemulsification on Intraocular Pressure in Primary Angle Closure Glaucoma (PACG) Patients At Phanat Nikhom Hospital, Chonburi Province

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT06252246
• Other study ID #: 5100500081212
• Status: Completed
• Start date: October 1, 2017
• Est. completion date: September 30, 2022

Study information

• Verified date: February 2024
• Source: Phanatnikhom Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

BACKGROUND: Primary angle closure glaucoma (PACG) is one of a leading cause of blindness worldwide including Thailand. This problem impact to the overall health of people and health care system. Treatment guidelines of each stage is differenced. Therefore, factors that affect to treatment should be explored to plan for taking care patients in the future.

OBJECTIVES: The study aimed to examine the effects of cataract surgery by phaco- emulsification on intraocular pressure and to determine the factors associated with intraocular pressure among primary angle closure glaucoma patients.

Description:

BACKGROUND: Primary angle closure glaucoma (PACG) is one of a leading cause of blindness worldwide including Thailand. This problem impact to the overall health of people and health care system. Treatment guidelines of each stage is differenced. Therefore, factors that affect to treatment should be explored to plan for taking care patients in the future.

OBJECTIVES: The study aimed to examine the effects of cataract surgery by phaco- emulsification on intraocular pressure and to determine the factors associated with intraocular pressure among primary angle closure glaucoma patients.

METHODS: A retrospective descriptive study was conducted in 121 patients with primary angle closure glaucoma who underwent phacoemulsification between October 1st 2017 and September 30th 2022. The preoperative and postoperative record form were used as the research instrument. Visual acuity, intraocular pressure, the number of glaucoma medications and ocular biometric parameters were collected. The descriptive statistics, Paired sample t-test, Repeated measures ANOVA and Multiple linear regression were used to analyze the outcomes. A p-value < 0.05 was considered statistically significant.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 121
• Est. completion date: September 30, 2022
• Est. primary completion date: September 30, 2022
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• age more 18 years old and not complication of cataract surgey

Exclusion Criteria:

• other eye diseases affect to visual defect

• previous ocular surgery

• complication of cataract surgery

• data record incomplete

Related Conditions & MeSH terms

• Glaucoma
• Glaucoma, Angle-Closure
• Primary Angle Closure Glaucoma

Intervention

Device:
• Phacoemulsification machine
type of phacoemulsification machine is different

Locations

Country	Name	City	State
Thailand	Phanatnikhom hospital	Chon Buri	Chonburi

Sponsors (1)

Lead Sponsor	Collaborator
Phanatnikhom Hospital

Country where clinical trial is conducted

Thailand, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	intraocular pressure	effects of cataract surgery by phacoemulsification on intraocular pressure and to determine the factors associated with intraocular pressure among primary angle closure glaucoma patients. Units of measure assessment intraocular pressure by non contact tonometry(intraocular pressure in millimeters of Mercury) at one week, one month, three months and six months postoperatively	six months