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Prevention of BMD Loss After THR clinical trials

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NCT ID: NCT02838121 Completed - Functional Outcomes Clinical Trials

Prevention of Periprosthetic Bone Loss After Total Hip Replacement by Annual Bisphosphonate Therapy

Start date: December 2009
Phase: Phase 3
Study type: Interventional

Periprosthetic bone loss caused by stress-shielding effect, a phenomenon of bone atrophy under mechanical unloading after THR implantation, further compromises the longevity of implant. The prospective randomized study is aimed to investigate the periprosthetic bone loss after primary total hip replacements.