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Body Weight Growth After Birth and Bronchopulmonary Dysplasia

Bronchopulmonary Dysplasia Clinical Trial

Official title:
Association of Body Weight Growth After Birth and Bronchopulmonary Dysplasia(BPD)

Clinical Trial Summary

Bronchopulmonary dysplasia (BPD) is one of the most common, complex, and severe diseases in preterm infants. BPD was first described as chronic pulmonary disease in survivors of severe respiratory distress syndrome (RDS) in 1967, which was also called as the "old" BPD. In recent years, the definition for BPD has developed a lot. The National Institute of Child Health and Human Development (NICHD) workshop in 2018 assessed BPD at 36 post-menstrual age (PMA) along with radiographic confirmation and used a severity grading of I-III. Although with effective surfactant supplement and oxygen support, BPD brings a great challenge to neonatologists.

Clinical Trial Description

Besides persistent inflammation, prolonged invasive ventilation and oxidative damage. body weight is the one of the most important factors to induce BPD. Poor extrauterine growth is commonly described in extremely preterm infants. But, the relationship of postnatal growth with BPD and respiratory morbidity is not entirely understood. The aim of the present study is to assess whether body weight growth after birth is the risk factor for BPD. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05053269
Study type Observational
Source Daping Hospital and the Research Institute of Surgery of the Third Military Medical University
Contact
Status Withdrawn
Phase
Start date October 1, 2021
Completion date December 31, 2024
View Details
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