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Vaginal Progesterone for the Prolongation of Pregnancy After Arrested Pre-term Labor

Preterm Labor Clinical Trial

Official title:
Vaginal Progesterone for the Prolongation of Pregnancy After Arrested Pre-term Labor - Randomized Double Blind Placebo Controlled Trial

Clinical Trial Summary

Patients diagnosed with arrested pre-term labor following tocolytics at 24-34 gestational weeks will be randomly allocated to receive either vaginal micronized progesterone 400 mg/day or no treatment.

Clinical Trial Description

Since progesterone derivatives are useful in preventing preterm labor in cases of risk factors or previous preterm labor, we hypothesize that they will also show efficacy in pregnancy prolongation in women whose preterm labor was arrested following tocolytic treatment. Patients diagnosed with arrested pre-term labor following tocolytics at 24-34 gestational weeks will be randomly allocated to receive either vaginal micronized progesterone 400 mg/day or no treatment. This study has the potential to find a treatment to prevent preterm labor and thus to reduce neonatal morbidity and mortality. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02430233
Study type Interventional
Source HaEmek Medical Center, Israel
Contact
Status Completed
Phase Phase 4
Start date December 19, 2018
Completion date February 27, 2023
View Details
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