Using a New Human Milk Fortifier to Optimize Feeding

Status Completed

Clinical Trial Summary

This study aims to compare the safety and efficacy of a new HMF and those of other HMF used before in very preterm infants.

Clinical Trial Description

Infants with fortified human milk feeding have the same rate of growth, lower incidence of nosocomial infections and feeding intolerance compared to those with formula feeding during hospitalization. However, the currently human milk fortifiers (HMF) have some nutritional components defects to meet the needs of very preterm infants. New HMF provide higher protein and fat, which are safe and well tolerate to use in preterm infants. Study on safety and efficacy of the new HMF is insufficient in Chinese preterm infant population. Our aims are to compare the safety and efficacy of a new HMF and other HMF used before in very preterm infants. Very low preterm infants with birth weights of 1000-1499g and gestational age 28+0 weeks to 31 + 6 weeks are included. Infants feeding with new HMF are in the experimental group. Infants feeding with other HMF are in the control group, a historically control group. Physical growth, nutritional indexes, incidence of feeding intolerance, and time to achieve full enteral feeding are compared between the two groups. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04283799
Study type	Interventional
Source	Children's Hospital of Fudan University
Contact
Status	Completed
Phase	N/A
Start date	March 16, 2020
Completion date	April 23, 2021

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