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Pressure Ulcer clinical trials

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NCT ID: NCT01211236 Completed - Pressure Ulcers Clinical Trials

Maggot Therapy for Wound Debridement

MAGGOT
Start date: February 2006
Phase: Phase 3
Study type: Interventional

The main objective of the trial was to study the efficacy of bagged larvae on wound debridement in comparison to classical treatments. The secondary outcome was to assess wound healing, treatment related pain, microbiological modifications, adverse events, comfort of the dressing and duration of wound care. We performed a randomized, double-blind, multicenter, controlled, prospective phase III trial in three referral institutional centers of hospitalized care in Caen, Lisieux and Lyon, France. A total of 120 patients with a non-healing fibrinous wound ≤ 40cm2, less than 2cm-deep, and an ankle-brachial pressure index (ABPI) ≥ 0.8 were included, from March 2005 to December 2008. During two weeks´ hospitalization, patients received either Maggot Debridement Therapy (MDT, changes of bagged larvae twice a week) or classical treatments (mechanical debridement and classical dressings performed three times a week). At discharge, classical dressings were applied and a follow-up visit performed at D30. Main outcome measure was the comparison of the reduction of fibrin percentage on wounds treated with MDT and classical treatments at D15. The percentages of fibrin were measured using a computerized planimetry software package, Canvas (ACD Systems, British Columbia, Canada), which enables the quantification of color surface variations in a wound after manual delimitation (using a mouse) on a series of photographic images.

NCT ID: NCT01208220 Terminated - Pressure Ulcer Clinical Trials

Effectiveness Study of Santyl Ointment to Treat Pressure Ulcers

Start date: June 2010
Phase: N/A
Study type: Interventional

Researchers at LSUHSC-S hope to learn the effects of the combination of a medication and a device which by themselves are effective for the treatment of wounds. You are being asked to take part in this study because you have a wound on your body which has not responded to standard treatments. The researchers will be studying whether the combination of two treatments will make wounds heal faster. For those in study, the investigators will treat them with a vacuum device on their wound. Also, some of the people in the study will receive a special ointment and researchers will use special tests to determine if the two treatments together are working better than just one treatment alone.

NCT ID: NCT01166828 Withdrawn - Spinal Cord Injury Clinical Trials

Pressure Ulcer Prevention for SCI Using a Tele Home Program

TELEPUPPS
Start date: January 2011
Phase: N/A
Study type: Interventional

NRI research focuses on nursing interventions that are patient-centered, culturally congruent, cost-effective and outcome-driven. High priority populations of interest are veterans with Spinal Cord Injuries (SCI). The development of innovative tele home techniques for preventing pressure ulcers in veterans with SCI is of high importance in the VA. Our findings may provide clinicians with improved methods for skin and wound assessment and more effective and efficient PUP strategies for Hispanic and non Hispanic veterans. The new model for primary care, the patient-centered Medical Home provides an exciting change in the VA that can benefit from the proposed project.

NCT ID: NCT01139879 Completed - Pressure Ulcers Clinical Trials

P400 for Stage II-IV Pressure Ulcers in Home and Extended Care

P400
Start date: June 2010
Phase: N/A
Study type: Interventional

To assess the efficacy of a pressure ulcer treatment mattress, the P400 mattress, in the treatment of multiple Stage II or one or more large Stage III or IV pressure ulcers in the home care and extended care (nursing home) environment.

NCT ID: NCT01113658 Withdrawn - Clinical trials for Diabetic Foot Ulcers

Clinical Evaluation of the SNaP Wound Care System

Start date: March 2010
Phase: N/A
Study type: Interventional

The purpose of this study is to assess the efficacy of design improvements of the Spiracur SNaP Wound Care System. This study prospectively evaluates the safety and efficacy of current and new design iterations of components of the FDA-cleared Spiracur SNaP Wound Care System in order to optimize safety, efficacy, and system performance.

NCT ID: NCT01107197 Completed - Pressure Ulcers Clinical Trials

Nutritional Support in Pressure Ulcer Patients

OEST
Start date: February 2010
Phase: N/A
Study type: Interventional

Pressure ulcers are frequently associated with malnutrition. Previous studies have reported that nutritional support can improve the healing rate of pressure ulcers but no attention has been clearly given to the nutritional status of the patient treated. Moreover, other investigators have suggested the additional healing power of some nutrients. Unfortunately, previous results have been unpowered by small sample size, poor monitoring of compliance to treatments and the confounding effect of other nutrients. The investigators aimed to test the effect and additional benefits of several micronutrients delivered through oral nutritional support on the healing rate of pressure ulcers in malnourished patients.

NCT ID: NCT01090076 Completed - Pressure Ulcer Clinical Trials

The Use of Specialised Amino Acid Mixture in Pressure Ulcer Wound Healing Rates- A Placebo Controlled Trial

Start date: April 2010
Phase: N/A
Study type: Interventional

This research aims to address the gap in the studies done and test the effects of a commercial mixture of 7 g of Arginine, 7 g Glutamine and 1.2 g HMB* twice a day on hard to heal pressure ulcers in an Asian patient cohort in an acute healthcare setting.

NCT ID: NCT01022216 Completed - Wound Healing Clinical Trials

Efficacy Study of a Bioelectric Dressing Used With Negative Pressure Wound Therapy to Treat Diabetic and Pressure Ulcers

Start date: August 2009
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine whether a bioelectric wound dressing, used in conjunction with Negative Pressure Wound Therapy (NPWT), is effective in the treatment of diabetic and pressure ulcers of the foot.

NCT ID: NCT01008254 Completed - Pressure Ulcers Clinical Trials

Interdisciplinary Mobility Approach To Reduction Of Facility-Acquired Pressure Ulcers

TEAM
Start date: September 2009
Phase: Phase 2/Phase 3
Study type: Interventional

Musical reminder will raise compliance with mobility in the long-term care setting and reduce facility-acquired pressure ulcers.

NCT ID: NCT00971048 Completed - Clinical trials for Diabetic Foot Ulcers

Evaluation of the Effects of HP828-101 Versus Standard of Care in the Management of Partial or Full Thickness Wounds

Start date: September 2009
Phase: N/A
Study type: Interventional

To compare HP828-101 to standard of care for the management of partial or full thickness wounds