Preoxygenation Clinical Trial
Official title:
The Effects of Setting Adjustable Pressure Limiting Valve (APL) to 5 cmH2O on Preoxygenation
The aim of this study is to investigate the effects of setting airway pressure release valve (APL valve) on the anesthesia workstation to 5 cmH2O during spontaneous breathing on preoxygenation. In this prospective study healthy volunteers are randomized in cross-over between spontaneous breathing with the APL valve on spontaneous position or spontaneous breathing with the APL valve on 5 cmH2O or CPAP (continous positive airway pressure) mode with 5 cmH2O PEEP (positive end expiratory pressure).
There are several methods to improve preoxygenation but most of them require advanced
anesthesia workstations. Therefore the investigators planned an an experimental study on
healthy volunteers to investigate the effects of a simple method on preoxygenation.
Healthy volunteers are randomized in cross-over between spontaneous breathing with the APL
valve on spontaneous position or spontaneous breathing with the APL valve on 5 cmH2O or CPAP
mode with 5 cmH2O PEEP.
The volunteers will breath through an anesthesia face mask. The fresh gas flow rate is 12
L/min, inspiratory fraction of oxygen is 100%. The exhaled gas (oxygen and carbon dioxide)
are monitored. The inspiratory and end expiratory fraction of oxygen will be recorded every
10 seconds.
The primary endpoint is the time to achieve end expiratory fraction of oxygen of 90% or
more.The secondary endpoint is the proportion of subject with end expiratory fraction of
oxygen of 90% or more after a 3 min period and the end expiratory fraction of oxygen at the
third minute.
;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT01018316 -
UMOX - New Device for Oropharyngeal Preoxygenation
|
N/A | |
| Completed |
NCT03310723 -
Pre-Oxygenation Techniques in Pregnancy
|
N/A | |
| Recruiting |
NCT04385511 -
Feasibility of Preoxygenation by Supraglottic Jet Ventilation Before Endotracheal Intubation
|
N/A | |
| Recruiting |
NCT04070404 -
Quality of Preoxygenation in Emergency Surgery
|
||
| Withdrawn |
NCT01232153 -
Preoxygenation Before Prehospital Tracheal Intubation With NIV Versus Balloon
|
N/A | |
| Recruiting |
NCT05846919 -
High Flow Oxygen in Preoxygenation During Rapid Sequence Induction in Infants and Small Children
|
N/A | |
| Terminated |
NCT03240614 -
PreOxygenation for EndoTracheal Intubations
|
N/A | |
| Completed |
NCT03087825 -
Preoxygenation Method With a Calibrated Leak
|
N/A | |
| Not yet recruiting |
NCT04148443 -
Impact of Preoxygenation Time on End-tidal Oxygen Concentration and on Hypoxic Events Occurring After Intubation in the Intensive Care Unit.
|
N/A | |
| Completed |
NCT02979067 -
Improvement of Oxygenation During Apnoea by i-THRIVE
|
N/A | |
| Recruiting |
NCT03802643 -
Preoxygenation Before General Anesthesia
|
||
| Completed |
NCT04596215 -
Benefit of the Oxygen Reserve Index for Control of Success of Preoxygenation in Adults
|
||
| Completed |
NCT03772574 -
Preoxygenation Using THRIVE Versus Facemask in Parturients
|
N/A | |
| Completed |
NCT03615417 -
High-Flow Nasal Cannula (HFNC) Preoxygenation in Obese Patients Undergoing General Anesthesia
|
N/A |