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Prenatal Diagnosis clinical trials

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NCT ID: NCT06081036 Not yet recruiting - Prenatal Diagnosis Clinical Trials

Normative Brain Volume Profiles From Multicenter Fetal MRI

MULTINORMFET
Start date: December 1, 2023
Phase:
Study type: Observational

Fetal brain MRI is an essential diagnostic tool to inform parents about the prognosis of abnormalities detected on routine ultrasound. Recent work has shown that brain MRI measurements at the antenatal stage are predictive of the child's postnatal development. However, this work remains limited to basic research, in part because of the lack of normative curves of brain tissue volume evolution from fetal MRI acquired in clinical routine. This project aims to fill this gap. For this purpose, the project will exploit fetal MRI scans acquired in 4 French hospitals (Marseille, Nice, Montpellier and Paris): MRI scans without abnormalities will be centralized for analysis, and families who have undergone these scans will be contacted to evaluate the development of their children after birth. Normative curves will be established by applying a set of treatments developed by the laboratory in Marseille collaborating in the project. Ultimately, these curves will help to clarify the diagnosis of fetuses by providing a quantitative characterization of the normality of brain measurements.

NCT ID: NCT05940363 Not yet recruiting - Prenatal Diagnosis Clinical Trials

The National Program for the Improvement of Management of Fetal Congenital Heart Disease in China

Start date: July 1, 2023
Phase:
Study type: Observational [Patient Registry]

To investigate and evaluate the capacity of prenatal screening, diagnosis and counseling of congenital heart disease in medical institutions in China, in order to understand the current status and existing problems of prenatal prevention and treatment capacity of congenital heart disease in China, and to obtain corresponding baseline data, so as to provide scientific basis for further improving prenatal screening and diagnosis policies in China.