Does Premature Luteinization Matter?

Premature Progesterone Rise Clinical Trial

Official title:

Does Measurement of Serum Progesterone on the Day of Trigger Matter?

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT03001492
• Other study ID #: Progesterone
• Status: Recruiting
• Phase: N/A
• First received: December 17, 2016
• Last updated: December 23, 2016
• Start date: December 2016

Study information

• Verified date: December 2016
• Source: Assiut University
• Contact: Osama Abdalmageed
• Email: drosamast1981[@]gmail.com
• Is FDA regulated: No
• Health authority: Egypt: Ministry of Higher Education
• Study type: Observational

Clinical Trial Summary

Elevation of serum progesterone on the day of ovulation triggering in IVF/ICSI cycles is suggested to be associated with compromized outcomes. Others found that this rise didnot affect the IVF/ICSI outcomes. It is still controversal if premature luteinization would affect the IVF/ICSI outcomes.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 200
• Est. primary completion date: June 2018
• Accepts healthy volunteers: No
• Gender: Female
• Age group: 18 Years to 42 Years

Eligibility

Inclusion Criteria:

• Planned fresh Embryo transfer

Exclusion Criteria:

• Cancelation of the embryo transfer for any reason

Study Design

Observational Model: Cohort, Time Perspective: Prospective

Related Conditions & MeSH terms

• Premature Birth
• Premature Progesterone Rise

Locations

Country	Name	City	State
Egypt	Osama Abdalmageed	Assiut	Non-US/Non-Canadian

Sponsors (1)

Lead Sponsor	Collaborator
Assiut University

Country where clinical trial is conducted

Egypt, 

References & Publications (1)

Sönmezer M, Pelin Cil A, Atabekoglu C, Ozkavukçu S, Ozmen B. Does premature luteinization or early surge of LH impair cycle outcome? Report of two successful outcomes. J Assist Reprod Genet. 2009 Mar;26(2-3):159-63. doi: 10.1007/s10815-009-9299-5. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Clinical pregnacy rate		14 days after the day of embryo transfer (ET)	No