Endometrial Gene Expression Profile in Controlled Ovarian Stimulation Cycles With Premature Luteinization

Premature Luteinization Clinical Trial

Official title:

Endometrial Gene Expression Profile in Controlled Ovarian Stimulation Cycles With Premature Luteinization

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT00447850
• Other study ID #: VLC-EL-1006- 307-2
• Status: Completed
• Phase: N/A
• First received: March 13, 2007
• Last updated: September 18, 2009
• Start date: April 2007
• Est. completion date: July 2009

Study information

• Verified date: September 2009
• Source: Instituto Valenciano de Infertilidad, IVI VALENCIA
• Contact: n/a
• Is FDA regulated: No
• Health authority: Spain: Comité Ético de Investigación Clínica
• Study type: Interventional

Clinical Trial Summary

Previous studies have suggested that premature luteinization (PL)during controlled ovarian stimulation (COS) decreases the implantation rate due to a negative effect on the endometrium receptivity. This study aims to describe the impact on endometrial gene expression of PL in GnRH antagonist and GnRH agonist cycles.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 0
• Est. completion date: July 2009
• Est. primary completion date: July 2009
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Female
• Age group: 18 Years to 35 Years

Eligibility

Inclusion Criteria:

• Oocyte donors

• Age between 18-35 years old

• BMI 18-29

• NORMOGONADOTROPHICS

• PROGESTERONE = 1.2 ng/ml on hCG day

Exclusion Criteria:

• PolyCystic Ovarian Syndrome (PCOS)

• Endometriosis

Study Design

N/A

Related Conditions & MeSH terms

• Premature Birth
• Premature Luteinization

Intervention

Procedure:
• endometrial biopsy

Locations

Country	Name	City	State
Spain	Ivi Valencia	Valencia

Sponsors (1)

Lead Sponsor	Collaborator
Instituto Valenciano de Infertilidad, IVI VALENCIA

Country where clinical trial is conducted

Spain,