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LATe Cerclage in High-risk Pregnancies (LATCH) — LATCH  

Premature Birth Clinical Trial

Official title:
Cervical Cerclage for Short Cervix at 24-26 Weeks of Gestation: a Randomized Controlled Trial

Clinical Trial Summary

The goal of this clinical trial is to determine whether cervical cerclage reduces the risk of preterm birth in patients with a short transvaginal ultrasound (TVU) cervical length (CL) ≤25mm between 24 0/7-26 6/7 weeks.

Clinical Trial Description

Singleton high-risk pregnancies < 24 weeks of gestation will be screened for enrollment and randomized, if a short TVU CL (≤25mm) is detected between 24 0/7 - 26 6/7 weeks, to either cervical cerclage or control (no cerclage). Aside from cerclage placement, management of included women will be the same including recommendation for continuing or initiating daily vaginal progesterone 200mg from randomization until 36 6/7 weeks. The primary outcome will be the incidence of preterm birth <37 weeks. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06036446
Study type Interventional
Source Thomas Jefferson University
Contact Moti Gulersen, MD, MSc
Phone 215-955-5000
Email moti.gulersen@jefferson.edu
Status Recruiting
Phase N/A
Start date November 10, 2023
Completion date February 2027
View Details
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