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Clinical Trial Details — Status: Terminated

Administrative data

NCT number NCT04906577
Other study ID # 19-PP-05
Secondary ID
Status Terminated
Phase N/A
First received
Last updated
Start date September 12, 2021
Est. completion date September 15, 2022

Study information

Verified date February 2024
Source Centre Hospitalier Universitaire de Nice
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

At birth, the study of interactions, particularly sensory interactions between a mother and her child, allows us to better understand the process of attachment. The sensory signals within the mother-infant dyad will lead to behavioural and metabolic adaptations in both individuals. Currently, the conditions of reception of a very premature newborn in the neonatal intensive care unit of the CHU of Nice lead to a separation between mother and child, with a reduction in sensory interactions. The immediate and long-term consequences of this "sensory rupture" are widely documented in the child, but little studied in the mother. The hypothesis at the origin of this work is that olfactory stimulations emanating from the newborn would allow a perceptive continuity between the newborn and his mother. In the pathological situation of the birth of a premature child, these stimulations would lead to neurobiological and behavioural modifications in the mother and would play a role in the attachment process.


Recruitment information / eligibility

Status Terminated
Enrollment 6
Est. completion date September 15, 2022
Est. primary completion date September 15, 2022
Accepts healthy volunteers No
Gender Female
Age group 18 Years and older
Eligibility Inclusion Criteria: - Immediate postpartum mothers of newborns with a term of < 33 weeks (32 weeks + 6 days) - primiparous mothers - Mothers with vaginal delivery, without oxytocin infusion after delivery - Mothers planning to breastfeed, with no maternal contraindication to breastfeeding Exclusion Criteria: - Substance abuse: active smoking at the time of delivery, alcohol, drugs - Use of medication: antidepressants or psychotropic drugs or centrally acting anti-emetics - Active depression or history of depression (under medical care with medical follow-up) in the year preceding the birth, on questioning - Chromosomal abnormality or congenital malformation of pre- or post-natal diagnosis in the newborn - Language barrier not allowing proper explanation of the protocol and responses to questionnaires

Study Design


Related Conditions & MeSH terms


Intervention

Other:
photography+odour
Daily from D0 to D5: a square of cotton cloth will be placed against the child's scalp by the childcare worker in charge of the child, then removed and placed in a sealed box containing a photograph of the child, which will then be given to the mother.
photography
A neutral smelling cloth will be placed with the child's photograph which will then be given to the mother.

Locations

Country Name City State
France CHU de Nice Nice

Sponsors (1)

Lead Sponsor Collaborator
Centre Hospitalier Universitaire de Nice

Country where clinical trial is conducted

France, 

Outcome

Type Measure Description Time frame Safety issue
Primary Change in ocytocine levels Day 4
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