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Extending CPAP Therapy in Stable Preterm Infants to Increase Lung Growth and Function

Premature Birth Clinical Trial

Official title:
Extending CPAP Therapy in Stable Preterm Infants to Increase Lung Growth and Function: A Randomized Controlled Trial

Clinical Trial Summary

This is a study to see if an extra 2 weeks of continuous positive airway pressure (CPAP) in stable preterm infants in the neonatal intensive care unit (NICU) can cause increased lung growth and lung function in the infants as measured at 6 months of age by pulmonary function testing.

Clinical Trial Description

This is a study to see if an extra 2 weeks of continuous positive airway pressure (CPAP) in stable preterm infants in the neonatal intensive care unit (NICU) can cause increased lung growth and lung function in the infants as measured at 6 months of age by pulmonary function testing. CPAP is a treatment widely used in the NICU in preterm infants right after they are born to help keep their lungs open/inflated. Although the benefit of CPAP after birth has been well studied, no one knows how long a stable preterm infant should stay on CPAP. The primary outcome of this study is to compare the lung volumes in the infants at 6 months of age by pulmonary function testing who were randomized to 2 extra weeks of CPAP in the NICU versus CPAP discontinuation, usual care. During the same pulmonary function test the investigators will also measure and compare how the infant's lungs diffuse gas. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04295564
Study type Interventional
Source Oregon Health and Science University
Contact
Status Active, not recruiting
Phase Phase 2/Phase 3
Start date January 10, 2020
Completion date July 1, 2024
View Details
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