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Premature Birth clinical trials

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NCT ID: NCT06019286 Not yet recruiting - COPD Clinical Trials

Novel Predictors of Premature Aging in COPD Patients

Start date: September 1, 2023
Phase:
Study type: Observational

•Examine whether COPD is associated with accelerated aging using a biological marker of aging and dermatological score

NCT ID: NCT06007547 Recruiting - Premature Birth Clinical Trials

Prophylactic Minimally Invasive Surfactant Evaluation

PreProMISe
Start date: January 1, 2024
Phase: Phase 4
Study type: Interventional

The purpose of this study is to explore the question: Does prophylactic administration of exogenous surfactant in the delivery room, using a minimally-invasive technique, improve outcome in preterm infants 22-29 weeks' gestation compared to rescue treatment using the same technique?

NCT ID: NCT06003959 Completed - Breastfeeding Clinical Trials

The Effect of Breastfeeding Support System

Start date: January 1, 2022
Phase: N/A
Study type: Interventional

This study was conducted to investigate the effect of a breastfeeding support system on breast milk quantity and mother-infant attachment in preterm infants. This randomized controlled experimental study was conducted in the Level III Neonatal Intensive Care Unit (NICU) of a hospital in eastern Turkey between January and June 2022. The population of the study consisted of preterm infants and their mothers who received treatment and care in the NICU between the dates of the study. The study sample consisted of 70 preterm infants (35 experimental, 35 control) and their mothers who met the research criteria.

NCT ID: NCT06000800 Completed - Cord Clamping Clinical Trials

Timing of Umbilical Cord Clamping in Preterm Neonates

Start date: November 18, 2021
Phase: N/A
Study type: Interventional

Umbilical cord clamping is an important intervention that routinely done for all neonates afterbirth. yet the optimal timing for this intervention remains controversial

NCT ID: NCT05997563 Recruiting - Preterm Labor Clinical Trials

Adjunctive Vaginal Progesterone in Management of Preterm Labor

Start date: August 16, 2023
Phase: Phase 4
Study type: Interventional

This study evaluates the addition of vaginal micronized progesterone effervescent to standard treatment in the treatment of preterm labor. Half of participants will receive vaginal micronized progesterone effervescent and standard treatment, while the other half will receive only standard treatment.

NCT ID: NCT05992181 Recruiting - Premature Birth Clinical Trials

Development of a Digital Tool for the Individualization of Speech Therapy Care for Premature Newborns

NEORTHO
Start date: September 15, 2023
Phase: N/A
Study type: Interventional

The study concerns the creation and implementation of a digital tool presenting the various orofacial stimuli that can be offered to premature newborns. This app is intended for parents, to allow them to play a more active role in their child's care, and provide them with special time with their child. The notion of pleasure is very important to us, and it's vital to help parents rediscover this feeling with their child. Different profiles will be created to individualize our recommendations, facilitate the understanding of orofacial stimuli, make them more concrete than drawings, and provide care adapted to each patient and improve the development of newborns through more regular orofacial stimulation.

NCT ID: NCT05990582 Enrolling by invitation - Preterm Birth Clinical Trials

The Alkmaar MLPTI Cohort Study: Outcomes at 9 Years

Start date: August 6, 2023
Phase: N/A
Study type: Interventional

Objective of the study: To examine cognition, motor function, executive functions, speech and language development, behaviour, psychosocial functioning,academic achievement, physical morbidities and growth of MLPTI at the age of 9 years and correlate this with BSID-III-NL scores,growth parameters and body composition at the age of 2 years. Study design: This study will be a prospective open, non-therapeutic exploratory cohort study and can be seen as a continuation on the study with protocol identification number NL50800.094.14, performed in the NWZ Alkmaar between 2014 and 2016. This was a study on growth and neurodevelopment of MLPTI in the first 2 years of life. Study population: The study population is a group of 200 moderate and late preterm children who were born in the NWZ Alkmaar between 2014 and 2016. 100 of these children participated in the aforementioned study on growth and neurodevelopment at the age of 2 years. The oldest children in this group will reach the age of 9 years in 2023. Brothers/sisters/friends of these children aged between 8 and 10 will be asked as control group (n=50). Primary study parameters/outcome of the study: The main study parameters are the IQ-scores of the WISC-V, the motoric scores of the Movement-ABC, the executive functions of the EMMA Toolbox, the presence of morbidities, the growth pattern and the mean blood pressure at 9 years of age. Secondary study parameters/outcome of the study: Secondary outcome parameters are the he behavioural and psychosocial outcomes of the CBCL and the SDQ scores, speech-and language-developmental scores of the CELF-5-NL and CCC-2-NL, MCH Feeding Scale and Teacher Report Form (TRF) scores. Other outcome parameters are the relation between the 9-year outcomes and the BSID-III scores at the age of 2, and the differences between the MLPTI and the control group. Furthermore, we aim to determine the relation between growth and body composition in the first two years of life and the waist circumference, growth parameters and blood pressure at the age of 9 years.

NCT ID: NCT05989438 Not yet recruiting - Prematurity Clinical Trials

Different Intervention Models of Premature Infants Based on the ICF Biopsychosocial Model

Start date: August 15, 2023
Phase: N/A
Study type: Interventional

Prematurity is an important risk factor for delayed neuropsychomotor development. The main objective of this study is to analyze the impact of different intervention models on the neuropsychomotor development of premature babies based on the ICF biopsychosocial model.

NCT ID: NCT05987800 Recruiting - Premature Birth Clinical Trials

Non-invasive Ventilation in Preterm Infants

Start date: February 1, 2023
Phase: N/A
Study type: Interventional

This is a prospective, observational cohort study. For the study part on noninvasive neurally adjusted ventilatory assist (NIV-NAVA) the design is interventional. For all participants prospective data collection will be conducted by chart review and by downloading ventilatory data from the ventilator. A registration of respiratory severity score will be done by a caregiver during the weaning period. This consists of a visual assessment of the work of breathing every 2 hours. For participants on NIV-NAVA consenting to the interventional part of the study a titration procedure will be conducted, afterwards serial electrical impedance tomography and lung and diaphragm ultrasound measurements will be done.

NCT ID: NCT05978674 Completed - Preterm Birth Clinical Trials

The Effect of Rocking Bed on Preterm Newborns

Start date: March 15, 2021
Phase: N/A
Study type: Interventional

The study was planned to determine the effect of rocking bed applied to preterm newborns on comfort, physiological parameters and cerebral oxygenase level (rSO2).