Prehypertension Clinical Trial
Official title:
Dietary Management and Aerobic Exercise on 24-hour Ambulatory Blood Pressure in Subjects With Prehypertension: Randomized, Single-blinded Clinical Trial
This is a multicenter, randomized, single-blinded clinical trial investigating the effect of dietary management and active aerobic exercise training on reduction of 24-hour ambulatory blood pressure in subjects with prehypertension.
While most guidelines defined arterial hypertension when office blood pressure(BP) ≥140/90 mmHg, epidemiological and observational studies showed that cardiovascular risk increases progressively from blood pressure levels as low as 115/75 mmHg and that prehypertension is likely to progress to hypertension. Regular aerobic exercise training is thought to be the cornerstone therapy for the prevention and treatment of hypertension. From a previous clinical trial, a 12-week aerobic exercise program reduced 24-hour and daytime ambulatory blood pressure in patients with resistant hypertension. Aerobic exercise and DASH (Dietary Approaches to Stop Hypertension) diet have been also recommended in subjects with prehypertension without a clear randomized, controlled clinical trial. The present trial, thus, seeks to evaluate the effect of dietary management and active aerobic exercise training, preferably moderate-intensity exercise, on 24-hour ambulatory blood pressure. ;
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT03644524 -
Heat Therapy and Cardiometabolic Health in Obese Women
|
N/A | |
Completed |
NCT02551640 -
Improving Physical Activity Through a mHealth Intervention in Cardio-metabolic Risk Patients
|
N/A | |
Recruiting |
NCT01483430 -
Effect of Ginseol Kg1 on Blood Pressure Lowering
|
Phase 3 | |
Completed |
NCT01637909 -
Korean Life-Style Modification Effects on Blood Pressure
|
N/A | |
Terminated |
NCT01295216 -
Use of Mobile Technology to Prevent Progression of Pre-hypertension in Latin American Urban Settings
|
N/A | |
Unknown status |
NCT01308983 -
Study of Amiloride on Vascular Phenotypes in Young Adults With Prehypertension
|
Phase 4 | |
Active, not recruiting |
NCT03596099 -
Rice Vinegar as an Intervention to Lower Blood Pressure in Adults With Prehypertension and 10-year CVD Risk <10%
|
N/A | |
Completed |
NCT04326686 -
Measuring Individual Responses to a Wholegrains and Nuts Intervention to Reduce Blood Pressure in Prehypertension
|
N/A | |
Completed |
NCT03898518 -
The Effects of a Jump Rope Exercise Program on Body Composition and Self-efficacy in Obese Adolescent Girls
|
N/A | |
Terminated |
NCT01983462 -
Vascular Dysfunction in Human Obesity Hypertension
|
Phase 2 | |
Completed |
NCT01458496 -
Health Coaching to Effect Lifestyle Behaviour Change
|
N/A | |
Completed |
NCT01472692 -
Study of Febuxostat Effect on Blood Pressure in Patients With High Normal Blood Pressure
|
Phase 4 | |
Completed |
NCT03266510 -
Inspiratory Muscle Strength Training to Improve Blood Pressure and Physiological Function
|
N/A | |
Completed |
NCT02998840 -
A Prospective Study of B244 Delivered as a Topical Spray to Determine Safety and Efficacy in Subjects With Elevated Blood Pressure
|
Phase 2 | |
Completed |
NCT01974570 -
Effect and Safety of Marealis RPC (Refined Peptide Concentrate) in Mild or Moderate Hypertensive Subjects
|
Phase 2 | |
Completed |
NCT02326766 -
Blood Pressure Lowering Effect of Supplementation With Korea Red Ginseng Associated With Reductions in Circulating Lp-PLA2 Activity and Lysophospatidylcholines and an Increase in Dihydrobiopterin in Prehypertensive Subjects
|
Phase 3 | |
Completed |
NCT01395329 -
Nebivolol and the Endothelin (ET)-1 System
|
Phase 4 | |
Completed |
NCT01331486 -
Nitric Oxide Mediated Vasodilatory Response to Hawthorn Standardized Extract
|
Phase 1 | |
Active, not recruiting |
NCT02371317 -
Stress Management for High Blood Pressure
|
N/A | |
Completed |
NCT03006471 -
Effect of Dapagliflozin on Blood Pressure Variability in Prediabetes and Prehypertension
|
Phase 4 |