High Altitude Clinical Trial
Official title:
The Effect of Different Altitude Levels on Spinal Anesthesia in Cesarean Section Surgery; Comparison of Anesthesia Parameters and Hemodynamic Changes
The aim of the researchers in this prospective study is to determine the differences, if any, in terms of anesthetic parameters among pregnant women who live at different altitudes and undergo cesarean section under neuraxial anesthesia under elective conditions and to contribute to the literature.
Increased intra-abdominal pressure during pregnancy increases the pressure in the epidural and spinal space and causes enlargement of the epidural veins. This may lead to easier increases in the anesthetic blockage level. For this reason, it is necessary to use the lowest possible dose of local anesthesia in these individuals compared to normal healthy individuals. The literature on the effect of altitude difference on central neuraxial block is limited. Based on studies showing changes in CSF volume and content in hypoxic conditions, According to the researchers, with the same amount of local anesthetic, the duration of sensory and motor blockade at sea level is thought to be equal to or longer than in mid-high regions. This study will be carried out among pregnant women who live in the city center at 3 different altitudes [0-10 m (Giresun), 810 m (Çorum), 1725 m (Van)] and undergo cesarean section under elective conditions. It will be performed in a multicenter, prospective, controlled, randomized manner in order to determine the differences, if any, among these pregnant women in terms of anesthetic parameters. ;
Status | Clinical Trial | Phase | |
---|---|---|---|
Enrolling by invitation |
NCT06133530 -
Human Milk Oligosaccharides (HMOs) and Gut Microbiota, Immune System in Antarctica
|
N/A | |
Completed |
NCT02233582 -
Effects of Non-steroidal Anti-inflammatory Drugs (NSAIDS) on Acclimatization to High Altitude
|
Phase 1 | |
Active, not recruiting |
NCT04604249 -
Prevalence of COVID-19 in High Altitude : Insights From the Highest City of the World
|
||
Not yet recruiting |
NCT05063643 -
Cardiotoxicity of Targeted Therapy for HER-2 Positive Breast Cancer Patients at High Altitude
|
||
Recruiting |
NCT05474287 -
SJOV vs. HFNO for Hypoxia During Procedural Sedation at High Altitudes
|
N/A | |
Completed |
NCT06392373 -
High Altitude Muscle Recovery
|
N/A | |
Completed |
NCT03851744 -
High Altitude and Exogenous Carbohydrate Oxidation
|
N/A | |
Completed |
NCT01830530 -
HIGH Altitude CArdiovascular REsearch in the ANDES
|
Phase 4 | |
Completed |
NCT06164665 -
Effects of Pioglitazone on Exogenous Carbohydrate Oxidation During Steady-State Exercise at High Altitude
|
Phase 4 | |
Recruiting |
NCT06393998 -
CO2 Supplement for Treatment of Acute Mountain Sickness
|
N/A | |
Not yet recruiting |
NCT06446427 -
The Effect of Acute High Altitude Exposure on Rescuer Performance and Patient Care
|
N/A | |
Completed |
NCT04915378 -
Hypoxia-altitude Testing to Predict Altitude Related Adverse Health Effects in Chronic Obstructive Pulmonary Disease (COPD) Patients
|
||
Completed |
NCT04290481 -
Oxygen Saturation and Perfusion Index ın Neonates at High Altitude
|
||
Completed |
NCT05798416 -
Effect of Inhalation of Low Dose CO2 on Exercise Performance at High Altitude
|
N/A | |
Recruiting |
NCT05115721 -
Establishing the Reference Interval for Pulse Oxygen Saturation in Neonates at High Altitude
|
||
Recruiting |
NCT06152744 -
Evaluation of Membrane Lung Function in High-altitude Regions
|
||
Recruiting |
NCT05304923 -
Supraglottic Jet Oxygenation and Ventilation for Gastrointestinal Endoscopy at High-altitude
|
N/A | |
Recruiting |
NCT04199650 -
Definition of ARDS in Qinghai Province: Verification of Berlin Definition Plateau Criteria
|