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Pregnancy Loss clinical trials

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NCT ID: NCT05430633 Completed - Appendicitis Clinical Trials

Laparoscopic Versus Open Appendectomy in Pregnancy

Start date: November 1, 2021
Phase:
Study type: Observational

The aim of this retrospective trial is to compare surgical and pregnancy outcomes of pregnant patients who underwent laparoscopic or open appendectomy for acute appendicitis.

NCT ID: NCT05344144 Completed - Anxiety Clinical Trials

EFT and Music on Psychological Development, Well-Being Status and Cortisol Level in Pregnant Women

EFT
Start date: June 1, 2020
Phase: N/A
Study type: Interventional

Emotional freedom technique and music were applied to pregnant women who experienced prenatal loss. Emotional freedom technique group, music group and control groups each consisted of 53 pregnant women.

NCT ID: NCT05073978 Completed - Preterm Birth Clinical Trials

B-vitamin Levels and Adverse Pregnancy Outcomes

Start date: December 1, 2020
Phase:
Study type: Observational

This prospective nested case-control study aims to examine the effects of blood vitamin B levels in first-trimester pregnant women on the pregnancy outcomes

NCT ID: NCT04910958 Completed - Covid19 Clinical Trials

Impact of COVID-19 Pandemic on Early Spontaneous Abortions and Early Termination of Pregnancy

Start date: January 6, 2021
Phase:
Study type: Observational

To see the impact the COVID-19 pandemic has had on early spontaneous abortions and early termination of pregnancy in the first trimester

NCT ID: NCT04017754 Completed - Clinical trials for Pregnancy Complications

Low Plasma Mannose Binding Lectin (p-MBL) Level is a Risk Factor for Recurrent Pregnancy Loss (RPL)

Start date: January 1, 2016
Phase:
Study type: Observational

The present study is based on the hypothesis, that recurrent pregnancy loss (RPL) is associated with abnormal plasma mannose binding lectin (p-MBL) level. Secondarily, p-MBL level may affect the reproductive and the perinatal outcome in the first pregnancy following RPL. Thus, the present study aim to examine whether MBL should be a biomarker for women at risk for RPL and, secondarily, affect the reproductive and perinatal outcome, and thereby help clinicians identify fragile women who need intensified perinatal care.

NCT ID: NCT04013035 Completed - Pregnancy Loss Clinical Trials

Cervical Length on Pregnancy Termination

Start date: January 1, 2016
Phase:
Study type: Observational

Cervical length is used as a parameter to predict cervical insufficiency and onset of labor. However, its role in predicting abortion induction is unclear.To investigate the impact of cervical length measurement and fetal viability on second trimester pregnancy termination duration in nulliparous pregnant women.

NCT ID: NCT03948022 Completed - Pregnancy Loss Clinical Trials

Luteal Support in Frozen-Thawed Embryo Transfer Cycles

Start date: June 30, 2021
Phase: Phase 4
Study type: Interventional

This study evaluates the clinical efficacy of 3 different luteal phase support in patients undergoing frozen-thawed embryo transfer cycles. Endometrium preparation will be hormone replacement in all cycles. Starting from day 11, group 1 will receive 100 mg micronized progesterone parenteral daily injections, group 2 will receive 90 mg bioadhesive gel vaginal twice daily and group 3 will receive 40 mg oral dydrogesterone daily tablets.

NCT ID: NCT03712683 Completed - Pregnancy Loss Clinical Trials

Thyroxin in Subclinical Hypothyroidism

Start date: September 1, 2016
Phase: N/A
Study type: Interventional

Subclinical hypothyroidism(SCH) is the elevated thyroid stimulating hormone (TSH) with normal free Thyroxine levels and it is a mild or compensated form of primary hypothyroidism. It has been suggested that SCH is more prevalent in infertile women (especially in women with ovulatory disorders.Various rates of SCH was reported in infertile women in different populations

NCT ID: NCT03585023 Completed - Pregnancy Loss Clinical Trials

Infections and Pregnancy Loss: Correlation Between Abortion and Silent Infections.

Start date: November 15, 2014
Phase:
Study type: Observational

Correlation between the presence of intracellular viruses/bacteria and the incidence of miscarriage during the first trimester of pregnancy.

NCT ID: NCT03442335 Completed - Miscarriage Clinical Trials

Implantation Test for Endometrial Receptivity

Start date: December 12, 2017
Phase:
Study type: Observational

Background Miscarriage is the most frequent complication of pregnancy and represents the spontaneous loss of the embryo or foetus before it is able to survive independently (24 weeks of gestation). It affects up to 50% of pregnancies with the vast majority (80%) occurring at pre-clinical stage before the woman recognises the pregnancy. Up to 5% of couples suffer recurrent miscarriage defined as 2-3 or more miscarriages leading to physical, emotional and financial consequences for couples, doctors and medical systems. Different maternal health problems (thyroid disease, sticky blood, autoimmune disease, anatomical anomalies of the womb) and embryo defects may be responsible for some of the miscarriages; however, more than 50% of the occurrences have no identifiable cause based on the current diagnostic tests. Aim The aim of the present research proposal is to understand the role of the lining of the womb in miscarriage and to explore the development of a potential implantation test that is cost-effective and may be implemented in clinical practice. Methods Over a period of two years, women who suffered recurrent miscarriage will be approached in the advanced miscarriage clinic at Birmingham Women's Hospital during their routine appointment. Participants will be invited to participate by undergoing chromohysteroscopy and/or a biopsy from the lining of the womb during an outpatient appointment. Chromohysteroscopy is based on a routine hysteroscopy which involves visualising the inside of the womb using a narrow telescope passed through the neck of the womb (cervix). "Chromo" comes from the fact that an iodine based dye will be injected to increase the power of the test. The biopsy will be taken using a narrow plastic tube passed through the cervix. It is a standard diagnostic test for women with abnormal bleeding. As part of the present research, different cells and molecules will be analysed from the biopsy sample.