The Effects of Vitamin D2 Supplement During Pregnancy

Pregnancy Early Clinical Trial

Official title:

The Effects of Vitamin D2 Supplement During Pregnancy on Postpartum Maternal and Fetal Vitamin D Levels: the Randomized Controlled Trial

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03743922
• Other study ID #: THAIVITD2
• Status: Completed
• Phase: N/A
• Start date: November 1, 2018
• Est. completion date: May 30, 2020

Study information

• Verified date: November 2018
• Source: Rajavithi Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The effects of vitamin D2 supplement during pregnancy on postpartum maternal and fetal vitamin D levels: the randomized controlled trial

Description:

Vitamin D structurally similar to steroids. Made from the skin. And metabolism of the liver, kidneys, vitamin D levels in the bloodstream are two types of vitamin D 2 (Ergocalciferol) and vitamin D 3 (Cholecalciferol) Vitamin D regulates calcium and phosphorus levels in the body. Including the accumulation of minerals in the bone. Vitamin D is important in the formation of bones and teeth and the normal growth of children, affects the reabsorption of amino acids in the kidneys, regulates the amount of calcium and phosphorus in the blood Vitamin D deficiency in pregnant affects the mother and baby example high maternal blood pressure during pregnancy, diabetes during pregnancy, increase birth body weight of baby. low calcium seizures Infants, baby have bones and growth disorders. Currently, no vitamin D supplement is used in pregnant women in Thailand who attend antenatal clinics. The researcher has proposed to study the effects of vitamin D supplement during pregnancy on postpartum maternal and fetal vitamin D levels by using vitamin D 20,000IU / week

Recruitment information / eligibility

• Status: Completed
• Enrollment: 60
• Est. completion date: May 30, 2020
• Est. primary completion date: November 15, 2018
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Female
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Women who have pregnant and ANC at Rajavithi hospital

• Women who have age at least 18 year

• Women who have Thai nationality

• Women who have pregnant of gestational age under 20week

Exclusion Criteria:

• Women who don't plan of delivered at Rajavithi hospital

• Women who have complication of pregnancy

• Woman who delivered before gestational age 37week

• Women who have abnormal kidney function

• Woman who have been used anticonvulsant drug or others form of vitamin d

• Women who have vitamin d allergy

Related Conditions & MeSH terms

• Pregnancy Early

Intervention

Drug:
• Calciferol
calciferol capsule
• Placebo
placebo capsule

Locations

Country	Name	City	State
Thailand	Rajavithi hospital	Bangkok

Sponsors (1)

Lead Sponsor	Collaborator
Rajavithi Hospital

Country where clinical trial is conducted

Thailand, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	effect of vitamin D 2 supplementation during pregnancy	To study the effect of vitamin D 2 supplementation during pregnancy on postpartum maternal and fetal vitamin D levels effects of vitamin D2 supplement during pregnancy on postpartum maternal and fetal vitamin D levels	within 30 minute after delivered
Secondary	vitamin D levels in maternal blood during pregnancy	To assess vitamin D levels in maternal blood during pregnancy	at first time ANC
Secondary	vitamin D levels in maternal blood after vitamin D supplementation	To assess vitamin D levels in maternal blood after vitamin D supplementation during pregnancy	within 30 minute after delivered