Clinical Trials Logo
  1. Home
  2. Pregnancy Complications
  3. NCT04989075

Oral Prophylactic Measures on the Occurrence of Pre-eclampsia (OP-PE) — OP-PE  

Pregnancy Complications Clinical Trial

Official title:
Effect of Oral Prophylactic Measures on the Occurrence of Pre-eclampsia (OP-PE) in High-risk Pregnant Women: A Cluster-randomized Controlled Trial

Clinical Trial Summary

Pre-eclampsia (PE) remains a major source of maternal and perinatal morbidity and mortality especially in low- and middle-income settings. PE, a pregnancy-specific hypertensive disorder, characterized by the development of placental endothelial dysfunction resulting in, among the most common diagnostic features, concomitant hypertension and proteinuria that may evolve into organs with fluctuating clinical specificities. Current studies indicate that periodontal disorders during pregnancy and particularly periodontal pathogens may be related to the risk of PE. Standard oral hygiene methods, based mainly on the joint use of toothbrushes and interdental brushes, reduce periodontal inflammatory risk, modulate of the dysbiotic oral microbiome. The purpose of the present study is to compare the PE outcomes in high-risk pregnant women receiving oral prophylactic measures to a control group. One specific question is addressed as follows according to the PICO principles: In high-risk pregnant women (Population), does oral prophylactic measures (Intervention) have a beneficial effect on PE parameters (Outcome) compared to pregnant women without any specific oral prophylactic measures (Control)?

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04989075
Study type Interventional
Source Claude Bernard University
Contact
Status Completed
Phase N/A
Start date March 15, 2022
Completion date July 25, 2023
View Details
See also
  Status Clinical Trial Phase
Active, not recruiting NCT03249896 - Web/Smartphone-based Lifestyle Coaching Program in Pregnant Women With Gestational Diabetes N/A
Completed NCT06338254 - Efficacy of Percussion Massage Therapy Applied to the Lower Extremity on Pain, Edema in Pregnant Women N/A
Recruiting NCT04825093 - Vitamin D Supplementarion in Pregnant Women at Risk and COVID-19 N/A
Completed NCT04739462 - SMS Maama Project COVID-19 N/A
Recruiting NCT04519593 - ABSOLUTELY: A Temporary Uterine Blood Supply Occlusion for Laparoscopic Myomectomy in Patients With UTErine LeiomYoma N/A
Recruiting NCT03313024 - Berlin-Brandenburg Pregnancy Cohort
Active, not recruiting NCT02577536 - PregSource: Crowdsourcing to Understand Pregnancy
Not yet recruiting NCT06357962 - Semi-permanent Acupuncture Effect on Cervical Ripening N/A
Not yet recruiting NCT03661749 - Urinary Protein to Creatinine Ratio in Term Pregnant Women N/A
Completed NCT02970721 - Use of Psychotropic Medications Among Pregnant Women With Bipolar Disorder
Completed NCT02191774 - Medical Abortion up to 10 Weeks Gestation at Home
Completed NCT01322529 - Nulliparous Pregnancy Outcomes Study: Monitoring Mothers-to-be N/A
Completed NCT00746551 - Intravenous Versus Oral Iron in Late Pregnancy: Results of Treatment Phase 4
Completed NCT00678080 - Metformin Versus Insulin in Pregnant Women With Type 2 Diabetes N/A
Completed NCT00634530 - Impact of a Nutritional Intervention Program for Weight Control During Pregnancy N/A
Completed NCT00197561 - Partnership on Nutrition and HIV/AIDS Research in Tanzania: Exploratory Research Study on Selenium and HIV Infection Phase 3
Completed NCT05527327 - Pannus Retraction for Ultrasound Evaluation of the Obese Gravida: A Pilot Study N/A
Recruiting NCT05551078 - Thrombophilia Screening After Severe IUGR
Recruiting NCT03100084 - PREdelivery Placental Biomarkers- Pregnancy and Delivery Outcome
Recruiting NCT06250192 - Educational TOolS for Pregnant Women With Diabetes Mellitus. N/A