Urinary Protein to Creatinine Ratio in Term Pregnant Women

Pregnancy Complications Clinical Trial

Official title: Urinary Protein to Creatinine Ratio in Term Pregnant Women: What is the Effect of a Clean Catch Urine

Status Not yet recruiting

Clinical Trial Summary

This study will determine the incidence of elevated U Pr/Cr in normal term pregnant women. In addition we will determine if a "clean catch" urine has an effect on the U Pr/Cr.

Clinical Trial Description

Clean catch urine should be used due to possible vaginal secretion contamination with falsely elevated U Pr/Cr ratio. However, no supporting reference was found in the article and no control group with random urine collection for comparison to clean catch specimen U Pr/Cr was included in their study. The original studies that validated spot Pr/Cr urine as a predictor of 24 -hour total urine protein used random non-clean catch random urines . They had an r value of .93-.99 in estimating total protein excreted in 24 hours. At our institution we use Siemens-base test to determine U Pr/Cr. In the product insert the company states that no special patient preparation is necessary.

Thus, this study will determine the incidence of elevated U Pr/Cr in normal term pregnant women. In addition we will determine if a "clean catch" urine has an effect on the U Pr/Cr. ;

Related Conditions & MeSH terms

• Pregnancy Complications

• NCT number: NCT03661749
• Study type: Interventional
• Source: St. Luke's Hospital, Pennsylvania
• Contact: James N Anasti, MD
• Phone: 484-526-8878
• Email: anastij@slhn.org
• Status: Not yet recruiting
• Phase: N/A
• Start date: September 2018
• Completion date: November 2019