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Pregnancy Complications clinical trials

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NCT ID: NCT06026969 Recruiting - Child Development Clinical Trials

Pregnancy and Early Neurodevelopmental Outcomes Following In Utero Lyme Disease Exposure

Start date: July 1, 2023
Phase:
Study type: Observational

The purpose of this pilot study is to assess the feasibility of longitudinal neurodevelopmental evaluation of fetuses and infants exposed to Lyme disease in utero. Participants with Lyme disease or Post-Treatment Lyme Disease Syndrome (PTLDS) will be recruited during pregnancy. Pregnancies will be monitored and infant development will be assessed from birth until age 18 months.

NCT ID: NCT06022458 Active, not recruiting - Clinical trials for Pregnancy Complications

Prenatal Sonographic Prediction of Placental Histology and Function

Start date: May 28, 2024
Phase:
Study type: Observational

The purpose of this two-phase observational study is to investigate the use of ultrasonography to predict placental pathology at the time of delivery.

NCT ID: NCT06019715 Completed - Clinical trials for Hypertensive Disorder of Pregnancy

Remote Postpartum Intervention Targeting Movement Behaviors After Hypertensive Disorders of Pregnancy

Start date: June 1, 2023
Phase: N/A
Study type: Interventional

The purpose of this study is to test the feasibility, acceptability, and preliminary efficacy of a postpartum physical activity intervention after a pregnancy complicated by a Hypertensive Disorder of Pregnancy. The study will also assess the effects of the remote postpartum intervention on blood pressure. To do this, we will recruit individuals that are 3-6 months postpartum a pregnancy complicated by a hypertensive disorder to participate in a 4-month health coaching intervention aimed to promote physical activity and was informed by formative work done previously.

NCT ID: NCT06002997 Completed - Clinical trials for Diabetes Mellitus, Type 1

Periodontal Status and Pregnancy or Delivery Complications in Type 1 Diabetes Mellitus Pregnant Women

Start date: May 3, 2012
Phase:
Study type: Observational [Patient Registry]

The results of contemporary studies suggest an association between inflammatory periodontal disease and pregnancy and delivery complications. The aim of this study was to assess the association between periodontal disease, clinical periodontal parameters and pregnancy or delivery complications in type 1 diabetes mellitus and non-diabetic pregnant women.

NCT ID: NCT05999851 Not yet recruiting - Preeclampsia Clinical Trials

Multiparametric Assessment of Maternal Vascular Function in the Prediction of Hypertensive Disorders of Pregnancy

EDIPE
Start date: September 2023
Phase: N/A
Study type: Interventional

The present study is a single-centre prospective study that will enrol pregnant women during their first trimester of pregnancy (11+0 - 13+6 weeks of gestation). During pregnancy, women will undergo standard clinical evaluation and management. During the two study visits (enrollment and 24+0 - 27+6 weeks of gestation) the investigators will perform arterial tonometry (Pulsepen) and in vivo darkfield microscopy (Glycocheck) to evaluate endothelial and vascular function. A urine sample and a blood sample for specific study analyses on metabolic profile, endothelial and angiogenic markers will be collected. Pregnancy outcomes will be collected at delivery and five years after delivery all the participants will be interview to collect long-term cardiovascular outcomes. Serum endothelial and angiogenic markers will be evaluated only in participants who will develop hypertensive disorders of pregnancy and in an equal number of controls matched for age and body mass index at the time of conception.

NCT ID: NCT05995106 Recruiting - Preeclampsia Clinical Trials

mHealth for Hypertensive Disorder of Pregnancy

Start date: October 2, 2023
Phase: N/A
Study type: Interventional

Objectives: We have developed a cardiovascular disease management application named Heart4U, with the capability of integrating with the Electronic Medical Records (EMR) system within the hospital. The main goal of this study is to evaluate the clinical effectiveness of a treatment approach that entails self-management of risk factors through a mobile application among pregnant individuals diagnosed with hypertensive cardiovascular conditions. Methods: Patients assigned to the app group receive assistance from the research team to install the Heart4U application and familiarize themselves with its usage. Both the app group and the usual care group continue to receive active treatment as previously administered (guideline-based prenatal care). Follow-up observations occur at each obstetric examination prior to delivery and are conducted again at the first month postpartum. The primary endpoint of observation pertains to the difference in systolic blood pressure between the enrollment and study completion time points.

NCT ID: NCT05980650 Active, not recruiting - Clinical trials for Pregnancy Complications

Reiki Effect on Risky Pregnants in Terms of Holistic Well-being, Prenatal, Maternal Attachment and Physical Symptoms

Start date: September 1, 2023
Phase: N/A
Study type: Interventional

Nurses should identify situations that may negatively affect mother-infant interaction from the prenatal period and mothers who experience these situations in order to ensure the establishment of secure attachment behavior. Then, they should cooperate with these mothers to eliminate negative situations or reduce their effects. It is also stated that practices such as meditation during pregnancy increase prenatal attachment. Despite the benefits of Reiki application, no study has been found on the use of reiki in risky pregnant women. In this study, the effect of remotely applied reiki on high-risk pregnant women on holistic well-being, prenatal, maternal attachment and physical symptoms will be examined.

NCT ID: NCT05977790 Recruiting - Sleeve Gastrectomy Clinical Trials

Determinant of Fetal Growth Retardation After Sleeve Gastrectomy: Involvement of Ghrelin

FG-SLEEVE
Start date: July 10, 2023
Phase:
Study type: Observational

The aim of the study is to determine, in pregnant women who have undergone sleeve gastrectomy (SG), whether ghrelin changes could be involved in in utero growth restriction (IUGR) and whether therefore a correlation between maternal ghrelin levels and birth weight is observed.

NCT ID: NCT05948319 Completed - Clinical trials for Pregnancy Complications

the Fetal Epicardial Thickness in Obese Pregnant Women (EFT)

EFT
Start date: October 1, 2022
Phase: N/A
Study type: Interventional

the effects of fetal EFT on fetal cardiac function and fetal and maternal outcomes were investigated in obese pregnant women compared with normal-weight pregnant women.

NCT ID: NCT05904002 Completed - Asthmatic Clinical Trials

Effect of Incentive Spirometery on Asthmatic Pregnant Women

Start date: September 20, 2020
Phase: N/A
Study type: Interventional

The purpose of this study is to determine the effect of the incentive spirometer on asthma during pregnancy.