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Pregnancy Complications clinical trials

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NCT ID: NCT03439956 Not yet recruiting - Clinical trials for Pregnancy Complications

Obstetric Outcomes After Transvaginal Specimen Extraction in Gynecological Laparoscopy

OUTSET-1
Start date: April 1, 2022
Phase:
Study type: Observational

One of the most important downsides of endoscopic surgery is the need to remove surgical specimens of different sizes through very small incisions. This step should ensure the complete retrieval of the surgical specimen with concomitant preservation of its integrity (if possible) in order to avoid intraabdominal contamination of potentially infected or malignant tissues. Possibilities for specimen extraction during laparoscopy include minilaparotomy, enlargement of an ancillary port, transumbilical extraction, and transvaginal extraction through posterior colpotomy. Although recent evidence has already suggested that transvaginal extraction through posterior colpotomy is a safe and feasible option, to date there are no published data about obstetric outcomes after this procedure. For this reason, the current study aims to evaluate obstetric outcomes between women that underwent transvaginal specimen extraction through posterior colpotomy and women who did not.

NCT ID: NCT03056274 Not yet recruiting - Clinical trials for Pregnancy Complications

Metformin in Intrahepatic Cholestasis of Pregnancy

METRIC
Start date: January 2019
Phase: Phase 2/Phase 3
Study type: Interventional

This is a pilot study aimed at comparing the effect of metformin versus ursodeoxycholic acid in women with intrahepatic cholestasis in pregnancy. The study will be conducted in three NHS hospital sites, over an 18 month period.

NCT ID: NCT02968316 Not yet recruiting - Clinical trials for Pregnancy Complications

Bioelectric Impedance Analysis and Pregnancy Outcomes

Start date: January 2017
Phase: N/A
Study type: Observational

This is a prospective observational study correlating Body Impedance Analysis (BIA) with pregnancy outcomes.

NCT ID: NCT02082795 Not yet recruiting - Clinical trials for Presentation; Breech, Complicating Pregnancy

Investigating Women's Views on the Management of a Breech Pregnancy

Start date: March 2014
Phase: N/A
Study type: Observational

The investigators aim to perform a qualitative study to explore the views of women with a breech presentation on their management in general, and the use of anaesthesia or analgesia for ECV in particular.

NCT ID: NCT01662596 Not yet recruiting - Pregnancy Clinical Trials

Detection of Risk Factors for Fetal Anomalies in a Rural Hospital Population

Start date: August 2012
Phase: N/A
Study type: Observational

The purpose of the study is to estimate the rate of risk factors for appearance of disease or fetal malformations in a population who turn to hospital "Hillel Yaffe" and examine whether there is a difference in the rate of early testing for diseases or birth defects in the fetus. Understanding the population and its risk factors, will allow specific reference to these risk factors to lowering them to eventually reduce the rate of congenital malformations in this population.

NCT ID: NCT01226823 Not yet recruiting - Clinical trials for Intrahepatic Cholestasis of Pregnancy

Ursodeoxycholic Acid And Cholestasis Of Pregnancy

CERTO
Start date: November 2010
Phase: Phase 3
Study type: Interventional

The study is a multicenter randomized double blind placebo controlled trial. The study will be conducted on pregnant women with a diagnosis of intrahepatic cholestasis of pregnancy (ICP) in third level hospitals (that are also Academic Hospitals). Pregnant women at the time of ICP diagnosis will be randomized in two groups: Group 1 - will receive placebo and obstetrical monitoring until delivery Group 2 - will receive UDCA at the dose of 20 mg/Kg/day and obstetrical monitoring until delivery. The hypotheses are that UDCA treatment will be superior to placebo and effective in: reducing the rate of prematurity; improving maternal biochemical parameters and symptoms.

NCT ID: NCT00567957 Not yet recruiting - Pre-Eclampsia Clinical Trials

Remifentanil for General Anesthesia in Preeclamptics

Start date: February 2008
Phase: Phase 4
Study type: Interventional

The purpose of this study is to determine whether remifentanil use in preeclamptic patients may blunt hemodynamic response to intubation during general anesthesia for cesarean section.