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Pregnancy Complications clinical trials

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NCT ID: NCT03347513 Recruiting - Clinical trials for Pregnancy Complications

Eradication of H-pylori in Pregnancy and Its Effect on Iron Replacement Therapy?

Start date: November 25, 2017
Phase: Phase 4
Study type: Interventional

the effect of eradication of H-pylori in pregnant patients with iron deficiency anemia on the level of hemoglobin after iron therapy.

NCT ID: NCT03313024 Recruiting - Preeclampsia Clinical Trials

Berlin-Brandenburg Pregnancy Cohort

BBPC
Start date: September 26, 2017
Phase:
Study type: Observational

This study will investigate the interplay of different immune cells and placental cells as well as their potential for the development of pregnancy complications. In particular, the translation of the uteroplacental syndrome into a maternal syndrome, considered in the multifactorial pregnancy disorder preeclampsia, will be investigated. Immune cell subtypes are causally involved in the formation and translation of preeclampsia by inducing an endothelial dysfunction which leads to cardiovascular damage.

NCT ID: NCT03228875 Recruiting - Clinical trials for Pregnancy Complications

Boston Birth Cohort Study

Start date: October 1998
Phase:
Study type: Observational [Patient Registry]

Early life exposures may lead to adverse effects on health in later life. The Boston birth Cohort study is designed to study a broad array of early life factors and their effects on maternal and child health outcomes.

NCT ID: NCT03220750 Recruiting - High Risk Pregnancy Clinical Trials

University Hospital Advanced Age Pregnant Cohort

UNIHOPE
Start date: March 28, 2017
Phase: N/A
Study type: Observational

The University Hospital Advanced Age Pregnant (UNIHOPE) Cohort is the major part of the National Key Research and Development Program on Reproductive Health & Major Birth Defects Control and Prevention Project, which is funded by the Ministry of Science and Technology of China. The Project is led by Prof. Zhao Yangyu, from the Department of Gynecology & Obstetrics, Peking University Third Hospital, and the UNIHOPE cohort is led by Prof. Jian-meng Liu, the Co-PI of the Project.

NCT ID: NCT03217656 Recruiting - Anemia Clinical Trials

The Jiaxing Birth Cohort in China

JBC
Start date: January 1999
Phase: N/A
Study type: Observational

The Jiaxing Birth Cohort (JBC) is the largest prospective cohort study to explore prenatal risk factors, early life feeding practice and growth pattern/ adiposity in Chinese children.Between 1999 and 2013, 338 413 mother-child pairs were recruited in Jiaxing area in south-east China.Children of the recruited women were followed up at 1-2, 3, 6, 9 and 12 months of age, and subsequently followed up every 6 months to 36 months of age (toddler stage), and every year to 6-7 years of age before they went to school (pre-school stage). Follow-up rate was 70.8% at the toddler stage and 68.9% at the pre-school stage up to June 2013.

NCT ID: NCT03152058 Recruiting - Clinical trials for Pregnancy Complications

IMPACT Study: IMProve Pregnancy in APS With Certolizumab Therapy

Start date: May 17, 2017
Phase: Phase 2
Study type: Interventional

This treatment trial evaluates the addition of an anti-tumor necrosis factor-alpha drug, certolizumab, to usual treatment (a heparin agent and low-dose aspirin) in pregnant women with antiphospholipid syndrome (APS) and repeatedly positive tests for lupus anticoagulant (LAC) to determine if this regimen will improve pregnancy outcomes. All enrolled patients will receive certolizumab, and pregnancy outcomes will be compared to those of women with APS and repeatedly positive tests for LAC enrolled in a previous study by the investigators.

NCT ID: NCT03100084 Recruiting - Clinical trials for Pregnancy Complications

PREdelivery Placental Biomarkers- Pregnancy and Delivery Outcome

PREPPeD
Start date: September 15, 2016
Phase:
Study type: Observational

The PREPPeD study proposes that predelivery placenta-derived maternal circulating biomarkers reflect placental health, capacity and ageing, and can help predict onset and complications of delivery both in complicated pregnancies as well as in clinically uncomplicated term/post-term pregnancies.

NCT ID: NCT02942719 Recruiting - Clinical trials for Pregnancy Complications

The Establishment and Application of the New Labor Progress Centered System of Reducing Cesarean Section Rates in China

Start date: January 2016
Phase: N/A
Study type: Observational

1. To describe the average labor curve and establish new labor progression standards. 2. Cesarean section rates: Based on big data, the investigator will introduce the international advanced Robson class method and identify the appropriate level of cesarean section rate for each type population. 3. Establishment of "Chinese maternal-fetal medical collaboration network" and APP to promote natural childbirth.

NCT ID: NCT02920593 Recruiting - Clinical trials for Gestational Hypertension

A Randomized Control Trial of Vitamin D Prophylaxis in the Prevention of Hypertensive Disorders of Pregnancy

Start date: October 2016
Phase: Phase 4
Study type: Interventional

The investigators aim to determine if Vitamin D prophylaxis in pregnancy reduces the incidence of hypertensive disorders of pregnancy.

NCT ID: NCT02744365 Recruiting - Preterm Birth Clinical Trials

Biobank on Prematurity, Preeclampsia and Other Pregnancy Complications

Start date: April 2015
Phase:
Study type: Observational

The Biobank includes data and biological specimens of women from three original studies: 1) First-trimester Prediction of Preeclampsia (PREDICTION Study, NCT02189148), 2) Pre-Eclampsia And growth Retardation, an evaluative Longitudinal study (PEARL Study, NCT02379832), 3) Effect of Low Dose Aspirin on Birthweight in Twins: The GAP Trial (NCT02280031) and 4)PREDICTION2: Prediction of Preeclampsia and other Pregnancy Complications Following Combined Iterative Screening.