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NCT06360601 Clinical Trial

Intravenous Labetalol Versus Hydralazine in Preeclampsia

Preeclampsia Severe Clinical Trial

Official title:
The Effect of Intravenous Infusion of Labetalol Versus Hydralazine on Cerebral Hemodynamics of Preeclampsia Patients Prospective Randamized Study

Clinical Trial Details — Status: Active, not recruiting

Administrative data
NCT number NCT06360601
Other study ID # 36264PR589/3/24
Secondary ID
Status Active, not recruiting
Phase Phase 1/Phase 2
First received
Last updated
Start date April 1, 2024
Est. completion date September 2024

Study information
Verified date April 2024
Source Tanta University
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

We study the effect of intravenous labetalol versus hydralazine in sever preeclampsia patients on cerebral blood flow and neurological outcome

Recruitment information / eligibility
Status Active, not recruiting
Enrollment 40
Est. completion date September 2024
Est. primary completion date September 2024
Accepts healthy volunteers No
Gender Female
Age group 25 Years to 45 Years
Eligibility Inclusion Criteria: - patient with clinical diagnosis of sever preeclampsia Exclusion Criteria: Patient with history of previous intracranial lesion Patient with history of heart disease/allergy to drug Patient with history of arrhythmia/anticoagulation Any craniotemporal lesion -

Study Design

Related Conditions & MeSH terms

Intervention

Drug:
• Labetalol Injection
Labetalol intravenous infusion 20ml/hr
• HydrALAZINE Injection
Hydralazine intravenous infusion 5mg/hr

Locations
Country Name City State
Egypt Faculty of Medicine Tanta

Sponsors (1)
Lead Sponsor Collaborator
Tanta University

Country where clinical trial is conducted

Egypt, 

Outcome
Type Measure Description Time frame Safety issue
Primary Cerebral blood flow Mean cerebral blood flow and cerebral perfusion pressure Pre intervention-after one hour of intervention
See also
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