Predictors of Burn Wound Healing Clinical Trial
Official title:
Use of Indocyanine Green (ICG) Fluorescence as a Noninvasive Means to Assess Burn Wound Severity and Healing
Hypothesis: Higher levels of perfusion on indocyanine green (ICG) fluoroscopy indicate
higher likelihood of burns healing whole lower levels of perfusion correlate with lower
likelihood of healing
Consented patients with burn injuries will be evaluated daily and along with continued wound
care will receive 5 mg of ICG (FDA approved dose) and their burns assessed fluoroscopically.
Perfusion will be quantified numerically as a percentage of normally perfused skin. No
changes to the actual care of the burn patient will be made as a result of the fluoroscopic
examination.
| Status | Completed |
| Enrollment | 3 |
| Est. completion date | August 2014 |
| Est. primary completion date | August 2014 |
| Accepts healthy volunteers | No |
| Gender | Both |
| Age group | 18 Years to 89 Years |
| Eligibility |
Inclusion Criteria: - Subjects aged 18-89 with indeterminate thickness burn wounds to trunk or extremities - Anticipated admission of greater than 3 days - Admission to the Timothy J Harner Burn Center - Informed consent Exclusion Criteria: - Known allergy for ICG, iodine or shellfish |
Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Diagnostic
| Country | Name | City | State |
|---|---|---|---|
| United States | Texas Tech University Health Sciences Center/University Medical Center | Lubbock | Texas |
| Lead Sponsor | Collaborator |
|---|---|
| Texas Tech University Health Sciences Center |
United States,
| Type | Measure | Description | Time frame | Safety issue |
|---|---|---|---|---|
| Primary | Perfusion rate and burn wound healing | The use of ICG fluoroscopic imaging and perfusion rates to anticipate wound healing will be assessed | 48-72 hrs. post admission to patient discharge | No |