Screening for Risk Factors of Prediabetes Among Adult Patients at Sohag University Hospital

PreDiabetes Clinical Trial

Official title: Screening for Risk Factors of Prediabetes Among Adults Patients at Sohag University Hospital

Status Recruiting

Clinical Trial Summary

• Prediabetes is an intermediate state of hyperglycemia with glycemic parameters above normal but below the diabetes threshold..

• during the average 3 years of follow-up Prediabetes is diagnosed based on laboratory tests: fasting plasma glucose level (100-125 mg/dl) ;HbA1c, (5.7-6.4%) or plasma glucose level after an oral glucose tolerance test ( 140-199 mg/dl).

• Reports estimate that more than 470 million people will have prediabetes by 2030.

• According to an expert panel of the American Diabetes Association, up to 70% of individuals with prediabetes will eventually develop diabetes.

• Observational evidence suggests as association between prediabetes and complications of diabetes such early nephropathy(10%) , small fiber neuropathy(18-25 %), early retinopathy (8-12%) and risk of macrovascular disease (52%) .

• Screening for prediabetes is designed to save lives or enhance an individual's quality of life by early detection so that screening will minimize the risk of developing diabetes or its complications .

Clinical Trial Description

• In this case control study we aim to screen for risk factors of prediabetes among adult patients to minimize the risk of developing diabetes or its complications .

• Prediabetes screening is also required to minimize medical costs such as hospitalization, outpatient care, surgery, medications, and laboratory test costs .

• Several studies had shown efficacy of lifestyle interventions in diabetes prevention by targeting obesity with increase in physical activity and dietary changes with a relative risk reduction of 40%-70% in adults with prediabetes ,also there is increasing evidence to prove the efficacy of pharmacotherapy in prevention of diabetes in adults with prediabetes ;

Related Conditions & MeSH terms

• Glucose Intolerance
• PreDiabetes
• Prediabetic State

• NCT number: NCT05864183
• Study type: Observational [Patient Registry]
• Source: Sohag University
• Contact: Nermeen F Ezzat, resident
• Phone: 01273878007
• Email: nerminfathy@med.sohag.edu.eg
• Status: Recruiting
• Start date: April 15, 2023
• Completion date: December 2023