Effects of Standing on Glycemia in Prediabetic Adults

Prediabetes Clinical Trial

Official title:

Acute Effects of Standing on Glycemia in Prediabetic Adults: A Pilot Study

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01884792
• Other study ID #: 1208M18741
• Status: Completed
• Phase: N/A
• First received: June 19, 2013
• Last updated: September 12, 2014
• Start date: March 2013
• Est. completion date: September 2013

Study information

• Verified date: September 2014
• Source: University of Minnesota - Clinical and Translational Science Institute
• Contact: n/a
• Is FDA regulated: No
• Health authority: United States: Institutional Review Board
• Study type: Interventional

Clinical Trial Summary

The study is a crossover, pilot trial examining the acute effects of standing on blood sugar in prediabetic, working adults. Participants will complete oral glucose tolerance testing, once while sitting and once while standing. They will also wear a continuous blood sugar monitor once while sitting at their desk for a week and once while using their desk as a sit-stand desk with a goal of standing intermittently for at least half of the work day. Physical activity levels will be measured with an accelerometer. The primary study hypothesis is that blood sugar will differ between the sitting and standing conditions for each of the tests performed.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 20
• Est. completion date: September 2013
• Est. primary completion date: July 2013
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: 18 Years to 65 Years

Eligibility

Inclusion Criteria:

• Fasting blood glucose >100 mg/dl

• Employed full-time working at least 35 hours/week

• Able to safely begin a light physical activity program

Exclusion Criteria:

• Heart disease

• Renal disease

• Peripheral neuropathy

• Retinopathy

• PAD

• Lower limb amputation

• pregnancy

• active substance abuse

• current smoker

• psychiatric disorder

• severe visual impairment

• immune-compromised individuals,

• enrollment in a physical activity study

• use of insulin or an insulin pump

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Crossover Assignment, Masking: Open Label, Primary Purpose: Basic Science

Related Conditions & MeSH terms

• Glucose Intolerance
• Prediabetes
• Prediabetic State

Intervention

Other:
• Sitting OGTT

• Standing OGTT

• Sitting CGM

• Standing CGM

Locations

Country	Name	City	State
United States	Department of Human Services	St. Paul	Minnesota

Sponsors (2)

Lead Sponsor	Collaborator
University of Minnesota - Clinical and Translational Science Institute	Mayo Clinic

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Blood sugar area under the curve	The area under the curve following the 2 hour blood sugar tests.	2 hours	No
Secondary	Accelerometer counts	Accelerometer counts in the 4 testing conditions.	4 hours and 2 5 day periods	No