Precocious Puberty Clinical Trial
OBJECTIVES:
Purify and characterize a testis-stimulating factor in the blood of adult volunteers who had
precocious puberty as boys.
PROTOCOL OUTLINE: Subjects are treated for 2 months with depot injections of leuprolide
acetate every 4 weeks and testosterone replacement every 2 weeks. Hormone levels are tested
every other week.
If luteinizing hormone and follicular-stimulating hormone levels are at or below detection
on day 56, blood is drawn for a testis-stimulating factor bioassay and subsequent factor
purification and characterization.
Volunteers are asked to repeat this 2-month procedure no more than 2 times every 12 months.
;
Primary Purpose: Screening
Status | Clinical Trial | Phase | |
---|---|---|---|
Not yet recruiting |
NCT01944475 -
Follow-up of Girls With Premature Thelarche and Precocious Puberty
|
N/A | |
Not yet recruiting |
NCT01944488 -
LH Response to GnRH Test in Prepubescent Girls Under 6 Years
|
N/A | |
Completed |
NCT00564850 -
Efficacy and Safety Study of Pamoate of Triptorelin in Children With Precocious Puberty
|
Phase 3 | |
Completed |
NCT00001181 -
Testolactone for the Treatment of Girls With LHRH Resistant Precocious Puberty
|
Phase 2 | |
Recruiting |
NCT04113070 -
Overweight and Obesity and Puberty Development Cohort Study
|
||
Recruiting |
NCT01601171 -
Genetics of Reproductive Disorders (Including Kallmann Syndrome) and Cleft Lip and/or Palate
|
||
Completed |
NCT00734279 -
Follicle-Stimulating Hormone (FSH) and the Onset of Puberty
|
Early Phase 1 | |
Recruiting |
NCT05338411 -
Effect of Exogenous Growth Hormone on Ocular Findings
|
||
Recruiting |
NCT06280807 -
Observation of Environment and Reproductive-Endocrine Effects
|
||
Completed |
NCT00001202 -
Treatment of Boys With Precocious Puberty
|
Phase 2 | |
Completed |
NCT04665713 -
Effect of Prevalence of BMI on Efficacy of Herbal Medicines in Girls' Sexual Precocity
|
||
Completed |
NCT02199587 -
The Effect of Medical Clown on the Pain and Anxiety Perception During LRH Analog Treatment or GH Provocation Test
|
N/A | |
Terminated |
NCT04502836 -
Evaluation of the Correlation Between Psychological Intervention, Including Providing Knowledge and Tools for Problems Solving, and the Anxiety Level of Female Patients Arriving to ACTH LRH Test - Pilot Study
|
N/A | |
Completed |
NCT00006174 -
Effects of Letrozole on Precocious Puberty Due to McCune Albright Syndrome
|
Phase 1 | |
Completed |
NCT02650141 -
Clinical Trial of Experienced Chinese Herbal Formulas on Different Types of Precocious Puberty
|
N/A | |
Completed |
NCT00909844 -
Effects of Triptorelin Pamoate in Children With Precocious Puberty - Follow up Study
|
Phase 3 | |
Completed |
NCT00004335 -
Study of Gonadotropin-Releasing Hormone Pulse Frequency in Sexual Maturation and in the Menstrual Cycle
|
N/A |