Pregnancy Clinical Trial
Official title:
Oncologic and Obstetric Outcomes After Conization for Uterine Cervical Lesion: A Cohort Study
This study is to investigate the oncologic and obstetric outcomes in patients with conization
for uterine cervical lesions from January 1, 2000 to January 1, 2019 in Peking Union Medical
College Hospital.
The primary objectives consist of following:
1. The cumulative incidences of precancerous lesions and cancers of lower genital tract in
patients who accepted conization for high grade intraepithelial neoplasia (HSIL),
carcinoma in situ and stage IA1 cancer (FIGO 2009)
2. The cumulative pregnancy rates in patients sparing the fertility
The secondary objectives consist of following:
1. The effects of surgical protocols (modified Sturmdorf method and "8" figure suture) and
energy equipment (cold knife and monopolar electrical cautery) on the oncologic and
obstetric outcomes, and on the histological components.
2. A full description of histological components of the conization specimens
3. The cytological and virus outcomes after conization, based on the thin prep liquid-based
cytology test (TCT) and high-risk human papillomavirus (HPV) testing
n/a
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