Precancerous Condition Clinical Trial
Official title:
Phase II Study of Thalidomide in Mastocytosis
RATIONALE: Thalidomide may stop the growth of systemic mastocytosis by blocking blood flow
to the disease.
PURPOSE: This phase II trial is studying how well thalidomide works in treating patients
with relapsed or progressive systemic mastocytosis.
OBJECTIVES:
Primary
- Determine the objective response rate at 6 months in patients with systemic
mastocytosis treated with thalidomide.
Secondary
- Determine the tolerability of this drug in these patients.
OUTLINE: This is a multicenter study.
Patients receive oral thalidomide once daily for 6 months in the absence of disease
progression.
;
Allocation: Non-Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
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