Papilloma Virus Vaccine Therapy in Treating Young Patients NCT00002454

Clinical Trial Details — Status: Unknown status

Administrative data
NCT number	NCT00002454
Other study ID #	CDR0000071657
Secondary ID	NJ-LAR-1NJ-M-41-
Status	Unknown status
Phase	Phase 2
First received	November 1, 1999
Last updated	July 23, 2011
Start date	December 1971

Study information
Verified date	January 2002
Source	National Cancer Institute (NCI)
Contact	n/a
Is FDA regulated	No
Health authority
Study type	Interventional

Clinical Trial Summary

RATIONALE: Vaccines made from papilloma virus cells may make the body build an immune response to and kill papilloma cells.

PURPOSE: Phase II trial to study the effectiveness of papilloma virus vaccine in treating young patients with recurrent papilloma of the larynx.

Description:

OBJECTIVES: I. Determine the immune response in patients with juvenile papilloma of the larynx treated with autogenous vaccine derived from each patient's own tumor.

OUTLINE: Patients receive autogenous papilloma vaccine intradermally and subcutaneously weekly for 20 weeks.

PROJECTED ACCRUAL: Not specified

Recruitment information / eligibility
Status	Unknown status
Enrollment	0
Est. completion date
Est. primary completion date
Accepts healthy volunteers	No
Gender	All
Age group	1 Year and older
Eligibility	DISEASE CHARACTERISTICS: Diagnosis of severe recurrent juvenile papilloma of the larynx requiring surgery at least 4 times per year Condition must have existed for more than 1 year PATIENT CHARACTERISTICS: Age: 1 and over Performance status: Not specified Life expectancy: Not specified Hematopoietic: Not specified Hepatic: Not specified Renal: Not specified PRIOR CONCURRENT THERAPY: See Disease Characteristics

Study Design

Related Conditions & MeSH terms

Intervention

Biological:
• autologous tumor cell vaccine

Locations
Country	Name	City	State
United States	New Jersey Medical School	Newark	New Jersey

Sponsors *(1)*
Lead Sponsor	Collaborator
University of Medicine and Dentistry of New Jersey

Country where clinical trial is conducted

United States,

References & Publications (2)

Oleske J, Fishman D, Cooper R, et al.: Autogenous vaccine in the treatment of laryngeal papilloma. In: Proceeding of the 12th International Congress of Chemotherapy, 1981. pp 1099-1101.

Oleske JM, Kushnick T. Juvenile papilloma of the larynx. Am J Dis Child. 1971 May;121(5):417-9. — View Citation

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Papilloma Virus Vaccine Therapy in Treating Young Patients With Recurrent Papilloma of the Larynx

Clinical Trial Details — Status: Unknown status

Administrative data

Study information