Pre-Term Clinical Trial
Official title:
Effect of Co-morbidities on the Development of Oral Feeding Ability in Pre-term Infants: a Prospective Study at Neonatology Unit of Assiut University Children Hospital
The aim of this study is to investigate the effect of co-morbidities on the timing of the achievement of full oral feeding in a cohort of pre-term infants and to evaluate their mode of feeding and feeding status at the time of hospital discharge.
Status | Not yet recruiting |
Enrollment | 160 |
Est. completion date | December 31, 2021 |
Est. primary completion date | October 31, 2021 |
Accepts healthy volunteers | No |
Gender | All |
Age group | N/A to 1 Day |
Eligibility | Inclusion Criteria: 1. A randomised sample of all newborns whose gestational age of < 37 weeks . 2. infants who will be admitted to the NICU of Assiut University Children Hospital between 1 May and 31 October 2021. Exclusion Criteria: 1. known congenital and/or chromosomal diseases. 2. death during hospitalisation, or transfer to another institution. |
Country | Name | City | State |
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n/a |
Lead Sponsor | Collaborator |
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Assiut University |
American Academy of Pediatrics Committee on Fetus and Newborn. Hospital discharge of the high-risk neonate. Pediatrics. 2008 Nov;122(5):1119-26. doi: 10.1542/peds.2008-2174. — View Citation
Capilouto GJ, Cunningham T, Frederick E, Dupont-Versteegden E, Desai N, Butterfield TA. Comparison of tongue muscle characteristics of preterm and full term infants during nutritive and nonnutritive sucking. Infant Behav Dev. 2014 Aug;37(3):435-45. doi: 10.1016/j.infbeh.2014.05.010. Epub 2014 Jun 20. — View Citation
Dodrill P, Donovan T, Cleghorn G, McMahon S, Davies PS. Attainment of early feeding milestones in preterm neonates. J Perinatol. 2008 Aug;28(8):549-55. doi: 10.1038/jp.2008.56. Epub 2008 Jun 26. — View Citation
Hwang YS, Ma MC, Tseng YM, Tsai WH. Associations among perinatal factors and age of achievement of full oral feeding in very preterm infants. Pediatr Neonatol. 2013 Oct;54(5):309-14. doi: 10.1016/j.pedneo.2013.03.013. Epub 2013 May 7. — View Citation
Jadcherla SR, Wang M, Vijayapal AS, Leuthner SR. Impact of prematurity and co-morbidities on feeding milestones in neonates: a retrospective study. J Perinatol. 2010 Mar;30(3):201-8. doi: 10.1038/jp.2009.149. Epub 2009 Oct 8. — View Citation
Lau C, Geddes D, Mizuno K, Schaal B. The development of oral feeding skills in infants. Int J Pediatr. 2012;2012:572341. doi: 10.1155/2012/572341. Epub 2012 Nov 5. — View Citation
Maggio L, Costa S, Zecca C, Giordano L. Methods of enteral feeding in preterm infants. Early Hum Dev. 2012 May;88 Suppl 2:S31-3. doi: 10.1016/S0378-3782(12)70011-7. Review. — View Citation
Van Nostrand SM, Bennett LN, Coraglio VJ, Guo R, Muraskas JK. Factors influencing independent oral feeding in preterm infants. J Neonatal Perinatal Med. 2015 Mar 12. [Epub ahead of print] — View Citation
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | The mean post-menstrual age in weeks at the time of starting and achieving full oral feeding will be evaluated | Statistical analysis will be made using SPSS version 12 software to assess the outcomes | Baseline |
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