Clinical Trials Logo

Clinical Trial Summary

This study aim to evaluate the effects of 16 weeks of multicomponent training on postural control, cardiovascular and musculoskeletal systems in pre-frail elderly through nonlinear and linear measurements.


Clinical Trial Description

Frailty syndrome is described as a clinical state of vulnerability to stress resulting from the decline of resilience and physiological reserves associated with aging. It is also characterized by a reduction of the interaction between systems and that would be reflected by a loss of physiological complexity. Physical exercise, especially the multi-component, is pointed out as a key element in the intervention of frail elderly individuals. However, it is still unclear whether the improvement in functional capacity observed with this type of training would be related to changes in the physiological complexity of these elderly individuals. The aim of this study is to evaluate the effect of multi-component training on the dynamics of the cardiovascular, motor, neuromuscular and physical activity levels of pre-frail elderly. Thirty-six pre-frail elderly individuals will be divided into intervention (IG, n = 18) and control (CG, n = 18) groups at three different moments (pre-intervention, post-intervention, 16 weeks, and follow-up of detraining of 6 Weeks). The complexity will be evaluated by calculating the entropy of the biological signals: a) heart rate, blood pressure (in supine and orthostatic conditions), b) oscillations of the pressure center (in open, closed eyes, after standing in a chair And under dual-task cognitive condition), c) torque oscillations of the knee extensor muscle group. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03110419
Study type Interventional
Source Universidade Federal de Sao Carlos
Contact
Status Completed
Phase N/A
Start date May 1, 2017
Completion date August 10, 2018

See also
  Status Clinical Trial Phase
Recruiting NCT04605809 - Effects of Combined Motor and Cognitive Training in Pre-frail Elderly N/A
Recruiting NCT02325245 - Effects of Metformin in Pre-frail Elderly Phase 3
Recruiting NCT02753582 - The Effect of SOD Enzyme on Frailty and HRQOL Among Indonesian Pre-frail Elderly: A Double Blind Randomized Controlled Trial Phase 4
Completed NCT01868945 - Dose Finding Study in Physically Frail Elderly to Measure 25(OH) Vitamin D Levels After Supplementation With Hy.D Calcifediol 25 SD/S and Vitamin D3 Phase 1
Completed NCT04847947 - The Effect of Cholecalciferol in Pre-frail Elderly Phase 3