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Pre-frail Elderly clinical trials

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NCT ID: NCT04605809 Recruiting - Pre-frail Elderly Clinical Trials

Effects of Combined Motor and Cognitive Training in Pre-frail Elderly

Start date: March 8, 2021
Phase: N/A
Study type: Interventional

The objective of this study is to investigate psychometric properties of dual-task walking assessments and compare effects of combined motor and cognitive training on physical fitness, brain fitness, and dual-task walking performance in pre-frail elderly. Specifically, we will investigate psychometric properties (i.e. reliability and validity) of dual-task walking assessments for pre-frail elderly (Aim 1). The second aim of this study is to compare the effects of combined motor and cognitive training vs. motor training alone vs. cognitive training alone vs. no intervention control on physical fitness, brain fitness, and dual-task walking performance in pre-frail elderly (Aim 2). The third aim of this study is to elucidate the effects of combined motor and cognitive training on patterns of cognitive motor interference in pre-frail elderly (Aim 3).

NCT ID: NCT02753582 Recruiting - Pre-frail Elderly Clinical Trials

The Effect of SOD Enzyme on Frailty and HRQOL Among Indonesian Pre-frail Elderly: A Double Blind Randomized Controlled Trial

Start date: April 2016
Phase: Phase 4
Study type: Interventional

The primary objective is to determine the effect of SOD enzyme on frailty and health related quality of life among Indonesian pre-frail elderly. The secondary objective is to determine the effect of SOD enzyme on anti-oxidant status, morbidity, and hospitalization among Indonesian pre-frail elderly. The study hypothesis: 1. SOD enzyme can improve frailty status and health related quality of life among Indonesian pre-frail elderly. 2. SOD enzyme can increase anti-oxidant serum status among Indonesian pre-frail elderly. 3. SOD enzyme can decrease morbidity among Indonesian pre-frail elderly. 4. SOD enzyme can decrease hospitalization events among Indonesian pre-frail elderly.

NCT ID: NCT02325245 Recruiting - Pre-frail Elderly Clinical Trials

Effects of Metformin in Pre-frail Elderly

Start date: March 2015
Phase: Phase 3
Study type: Interventional

The purpose of this study is to investigate the effects of metformin to prevent frailty in pre-frail non-diabetic elderly. Several outcomes measured in this study are frailty status, quality of life, handgrip strength, gait speed, and serum myostatin levels. We hypothesize that metformin for 16 weeks could prevent frailty in pre-frail elderly.