Pre-Exposure Prophylaxis Clinical Trial
Official title:
Adapting Effective mHealth Interventions to Improve Uptake and Adherence of the HIV Pre-exposure Prophylaxis (PrEP) in Thai Young Men Who Have Sex With Men (MSM).
The goal of this study is to develop and pilot test technology-based interventions to promote Pre-exposure Prophylaxis (PrEP) uptake and adherence among Thai young men who have sex with men (YMSM).
Motivational Enhancement System for Adherence (MESA) is a computer-based motivation invention, based on the Information-Motivation-Behavioral Skills (IMB) model and Motivational Interviewing (MI) principles, used to promote adherence among HIV-positive youth initiating antiretroviral treatment. In this study, the team will adapt and develop MESA to focus on PrEP uptake and adherence, which will be called Motivational Enhancement System for PrEP Uptake and Adherence (MES-PrEP). Motivational Interactive Text Messaging (MTM) will be integrated with MES-PrEP to provide ongoing support to maintain the individual's motivation for behavior change. Both interventions will be developed and refined based upon the inputs from YMSM through focus group discussion and youth advisory board. The Investigators propose to pilot randomized controlled trial (RCT) to evaluate the feasibility, acceptability, and preliminary efficacy of an intervention combining MES-PrEP and MTM to increase PrEP uptake and adherence among Thai YMSM. Eligible YMSM will be randomized to receive either the intervention plus the standard PrEP counseling or standard PrEP counseling, and followed for 6 months with assessments at baseline, month 1, 3 and 6. ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT06162897 -
Case Management Dyad
|
N/A | |
| Active, not recruiting |
NCT04064567 -
Linking High-Risk Jail Detainees to HIV Pre-Exposure Prophylaxis: PrEP-LINK
|
N/A | |
| Completed |
NCT03805451 -
Life Steps for PrEP for Youth
|
N/A | |
| Not yet recruiting |
NCT06046079 -
Predictors of Health Service Utilizations Among Key Population in Washington DC
|
||
| Recruiting |
NCT05929521 -
Centering Those Engaged in Transactional Sex: A PrEP Innovation for Getting To Zero
|
Early Phase 1 | |
| Not yet recruiting |
NCT06408142 -
Universal Test and Connect for HIV Service Delivery in South Africa
|
||
| Recruiting |
NCT05165745 -
Stick2PrEP Cisgender Women and Trans Individuals
|
N/A | |
| Completed |
NCT03177512 -
LYNX: A Novel Mobile App to Support Linkage to HIV/STI Testing PrEP for Young Men Who Have Sex With Men
|
N/A | |
| Completed |
NCT04205487 -
PrEP Readiness Interventions for Supporting Motivation
|
N/A | |
| Completed |
NCT03965221 -
Comparison of Men's Prevention Apps to Research Efficacy
|
N/A | |
| Completed |
NCT05417620 -
Le Kip Kip: A Campaign to Change Social Norms and Build Sustainable Demand for PrEP Among Women in South Africa
|
N/A | |
| Completed |
NCT03226873 -
Peer Outreach and Navigation Intervention to Increase PrEP Uptake Among Women at High Risk for HIV
|
N/A | |
| Completed |
NCT03493555 -
Optimizing PrEP Adherence for Young Men Who Have Sex With Men
|
N/A | |
| Recruiting |
NCT05728034 -
Information Seeking About Pre-exposure Prophylaxis
|
N/A | |
| Completed |
NCT03995862 -
Evaluation of Pre-Exposure Prophylaxis Against HIV in Alpine Region
|
||
| Completed |
NCT03729570 -
Electronic Pre-exposure Prophylaxis (PrEP) Initiation and Maintenance Home Care System
|
N/A | |
| Completed |
NCT04248790 -
Design and Development of a Mobile App to Improve Adherence to Pre-exposure Prophylaxis in Men Who Have Sex With Men
|
N/A | |
| Recruiting |
NCT05614492 -
Development and Evaluation of a PrEP Decision Aid for Women Seeking Domestic Violence Services in Baltimore
|
Phase 2/Phase 3 | |
| Completed |
NCT04712994 -
PrEPARE: PrEP in Pregnancy, Accelerating Reach and Efficiency
|
N/A | |
| Completed |
NCT04664998 -
Alignment of PrEP Use With HIV Risk in Young Women and Men
|
Phase 4 |