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NCT06214702 Clinical Trial

Serpin C and Soluble Fms-like Tyrosine Kinase-1 Levels in Normotensive Pregnant Women May Predict the Development of Preeclampsia

Pre-Eclampsia Clinical Trial

Official title:
Deregulated Serum Levels of Serpin C and Soluble Fms-like Tyrosine Kinase-1 Might Predict the Development of Preeclampsia in Normotensive Pregnant Women

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT06214702
Other study ID # RC 7.1.2024
Secondary ID
Status Completed
Phase
First received
Last updated
Start date January 7, 2023
Est. completion date November 15, 2023

Study information
Verified date January 2024
Source Benha University
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

Evaluation of the predictability of estimated levels of Serpin C, sFlt-1 and placental growth factor (PLGF) in blood samples obtained during the 1st trimester from normotensive pregnant women for identification of women liable to develop PE during the course of pregnancy.

Recruitment information / eligibility
Status Completed
Enrollment 60
Est. completion date November 15, 2023
Est. primary completion date May 12, 2023
Accepts healthy volunteers Accepts Healthy Volunteers
Gender Female
Age group 25 Years to 45 Years
Eligibility Inclusion Criteria: - Normotensive pregnant women had singleton fetus presenting during the 1st trimester - free of exclusion criteria Exclusion Criteria: - Age - Sex - Hypertension

Study Design

Related Conditions & MeSH terms

Intervention

Diagnostic Test:
• ELISA
ELISA estimation of PLGF, sFlt-1 and Serpin C

Locations
Country Name City State
Egypt Banha University Banha El- Qalyobia

Sponsors (1)
Lead Sponsor Collaborator
Benha University

Country where clinical trial is conducted

Egypt, 

Outcome
Type Measure Description Time frame Safety issue
Primary Role of Biomarkers in detection of GHTN The predictability of serum biomarkers' levels estimated at enrolment for the development of GHTN. 9 months
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