Androgens Level in the Third Trimester of Pregnancy in Patients With Preeclampsia

Pre-Eclampsia Clinical Trial

Official title: Androgens Level in the Third Trimester of Pregnancy in Patients With Preeclampsia

Status Completed

Clinical Trial Summary

This study aims to compare between androgens level (serum total and free testosterone) in women with preeclampsia and normal ones in the third trimester of pregnancy (28-40 weeks).

Clinical Trial Description

Methodology:

All women in this study will be subjected to:

• All women are candidates for this study according to inclusion and exclusion criteria.

• History taking with special emphases on last menstrual period to determine the exact Gestational age.

• A reliable date is defined as the occurrence of regular menstrual cycles (28±7 days) in patients who have not taken oral contraceptives during the three months before conception and have no irregular bleeding.

• General and abdominal examination for each patient to determine those patients matching with the inclusion criteria.

• Preeclampsia refers to the new onset of hypertension (systolic blood pressure ≥140 mmHg ,or diastolic blood pressure≥ 90 mmHg ,or both, measured on two occasions > 6 hours apart) and either proteinuria or end organ dysfunction after 20 weeks of gestation in a previously normotensive woman.

• At Ain Shams University Hospitals, the investigator will use ELISA based test system intended for the quantitative measurement of total and free testosterone for patients of both groups. ;

Study Design

Observational Model: Case Control, Time Perspective: Retrospective

Related Conditions & MeSH terms

• Eclampsia
• Pre-Eclampsia

• NCT number: NCT02992145
• Study type: Observational
• Source: Ain Shams Maternity Hospital
• Status: Completed
• Phase: N/A
• Start date: March 2016
• Completion date: December 2016