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Pre-eclampsia clinical trials

View clinical trials related to Pre-eclampsia.

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NCT ID: NCT03299777 Recruiting - Pre-Eclampsia Clinical Trials

Correlation Between Changes in Liver Stiffness and Preeclampsia as Shown by Fibroscan

Start date: September 5, 2017
Phase: N/A
Study type: Observational

Compare the Fibroscan results of preeclamptic women to normal controls and to find out if the changes are reversible after labor. Materials and Methods

NCT ID: NCT03298802 Recruiting - Pre-Eclampsia Clinical Trials

Postpartum Management of Hypertension in Pregnancy With Hydrochlorothiazide

Start date: November 21, 2017
Phase: Phase 3
Study type: Interventional

Postpartum prophylactic HCTZ administration for prevention and relapse of preeclampsia or gestational hypertension.

NCT ID: NCT03289611 Completed - Preeclampsia Clinical Trials

Preeclampsia Ratio (sFlt-1/PlGF)

PRECOG
Start date: April 26, 2018
Phase: N/A
Study type: Interventional

The aim of the PRECOG study is to determine in a prospective interventional randomized study whether the implementation of a predictive test based on the sFLT-1/PlGF ratio improves perinatal care and reduces costs, in patients with suspected preeclampsia before 35 weeks of gestation.

NCT ID: NCT03269110 Enrolling by invitation - Asthma Clinical Trials

Folic Acid Clinical Trial: Follow up of Children (FACT 4 Child)

Start date: July 1, 2017
Phase:
Study type: Observational

FACT 4 Child is a follow up study of mothers who participated in the Folic Acid Clinical Trial (NCT01355159) and their children at 4-6 years of age to determine the effect of high dose folic acid supplementation on social impairments associated with Autism Spectrum Disorders (ASDs), and deficiencies in a range of executive function and emotional and behavioural problems in young children, and the risk of death.

NCT ID: NCT03262961 Recruiting - Pre-Eclampsia; Mild Clinical Trials

Use of Sildenafil Citrate in Management of Mild Pre-eclampsia

Start date: September 15, 2016
Phase: Phase 2/Phase 3
Study type: Interventional

- Mild pre-eclampsia represents 75% of cases with pre-eclampsia, possible progression to severe pre-eclampsia makes mild pre-eclampsia a serious problem that requires attention. - Previous studies have shown that expectant and conservative management of pre-eclampsia in the context of extreme prematurity may improve perinatal outcomes. Indeed, it has been estimated that for each additional day of pregnancy prolongation between 24 and 32 weeks of gestation, there is a nonlinear corresponding gain of 1% in fetal survival. - Sildenafil citrate has been used for increasing utero-placental perfusion in cases with intrauterine growth restriction, which makes it a promising drug in management of mild pre-eclampsia.

NCT ID: NCT03258125 Completed - Preeclampsia Clinical Trials

miRNA-452 in Patients With Preeclampsia and Its Correlation With MMP-9

Start date: January 1, 2019
Phase:
Study type: Observational

Preeclampsia is a pregnancy related disease characterized by the new onset of hypertension and proteinuria after 20 weeks of gestation in previously normotensive women. PE is one of the most challenging diseases in obstetrics worldwide that affects 2-8 % of pregnancies causing both morbidity and mortality of both mother and fetus.

NCT ID: NCT03252496 Completed - Cesarean Section Clinical Trials

Combined Colloids And Crystalloids Versus Crystalloids in Women With Preeclampsia Undergoing Cesarean Delivery

Start date: August 19, 2017
Phase: N/A
Study type: Interventional

This study will compare between combination of colloids/crystalloids and crystalloids in women with preeclampsia undergoing elective cesarean delivery under spinal anesthesia

NCT ID: NCT03246542 Completed - HELLP Syndrome Clinical Trials

Promising Bimarker Prediction of Outcome of HELLP Syndrome.

Start date: January 1, 2015
Phase: N/A
Study type: Observational [Patient Registry]

HELLP syndrome is a life-threatening obstetric complication usually considered to be a variant or complication of pre-eclampsia. And may occasionally be confused with other diseases complicating pregnancy such as acute fatty liver of pregnancy, gastroenteritis, hepatitis, appendicitis, gallbladder disease, immune thrombocytopenia, lupus flare, antiphospholipid syndrome, hemolytic-uremic syndrome, thrombotic thrombocytopenic purpura, and nonalcoholic fatty liver disease. The distinction between thrombotic thrombocytopenic purpura-hemolytic uremic syndrome and severe preeclampsia is important for therapeutic and prognostic reasons. However, the clinical and histological features are so similar that establishing the correct diagnosis is often difficult; furthermore, these disorders may occur concurrently.

NCT ID: NCT03245970 Withdrawn - Preeclampsia Clinical Trials

Impedance Cardiography to Decrease the Risk of Preeclampsia

Start date: April 24, 2017
Phase: Early Phase 1
Study type: Interventional

To determine if the use of impedance cardiography can identify appropriate medications for use in treating chronic hypertensive patients to decrease the risk of preeclampsia.

NCT ID: NCT03237000 Not yet recruiting - Preeclampsia Clinical Trials

Effect of Administering Intravenous Magnesium Sulfate on Fetal Cardiotocography and Neonatal Outcome in Preeclamptic Patients

Start date: August 1, 2017
Phase: Phase 4
Study type: Interventional

Admission CTG for 20 minutes Settings on a CTG machine was standardised to enable a consistent approach of interpretation of traces. Paper speed of 3cm per minute will be adopted. Maternal heart rate was recorded and noted on CTG. Following birth date, time and mode of delivery will be labelled on CTG. Magnesium sulphate was administered by continuous intravenous infusion according to our hospital protocol as follows: - Loading dose: 4-6 gm of magnesium sulphate diluted in 100 mL of IV fluid administered over 15-20 min. - Maintenance dose: 2 gm/hr in 100 mL of IV infusion to be continued for 24 hours after delivery. Another 20 minutes CTG strip will be performed 20 minutes after administration of IV loading MgSO4, 7H2O and thus ensuring that MgSO4 has reached peak serum levels