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A Study for Pre-diabetic Patients With Cholesterol Lowering Drugs — SIROCO  

Pre-diabetes Clinical Trial

Official title:
Effects of Simvastatin and Rosiglitazone Combination in Patients With the Metabolic Syndrome.

Clinical Trial Summary

The purpose of this research study is to examine if a combination of a cholesterol lowering-drug, simvastatin, with a sugar-lowering drug called rosiglitazone is more effective in improving vascular inflammation (irritation of the vessels that transport your blood) and other cardiovascular risk factors than the taking of simvastatin alone.

Clinical Trial Description

Age 21-75 years Metabolic syndrome (must have 3 of the 5 components) elevated waist circumference >40inches in men, >35 inches in women elevated triglycerides >150mg/dL reduced HDL <40mg/dL in men<50 in women elevated blood pressure >130mmHg systolic, or >85mmHg diastolic elevated fasting glucose >100mg/dL ;

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator)

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00831129
Study type Interventional
Source University of Chicago
Contact
Status Completed
Phase Phase 2/Phase 3
Start date September 2006
Completion date April 2011
View Details
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