Posttraumatic Stress Disorders Clinical Trial
Official title:
Double Blind, Placebo-Controlled Trial of THC as add-on Therapy for PTSD
Stress Disorder (PTSD) is a chronic and debilitating anxiety disorder which is widespread in
every social level and is very prevalent in outpatient and inpatient settings.
A recent open-label study showed that the synthetic cannabinoid receptor agonist Nabilone
had beneficial effects abolishing or greatly reducing nightmares that persisted in spite of
treatment with conventional PTSD medications. Furthermore, a big number of patients
suffering from chronic PTSD report using smoked marijuana because its tranquilizing effect
and sleep quality improvement. According to clinical and epidemiological data different
derivates from the cannabis plant are illegally and pervasively consumed by PTSD patients in
order to reduce distress.
The aim of the proposed study is to broaden the previous observations and to measure the
extent to which Δ 9-THC will bring to significant improvement on the full spectrum of PTSD
symptoms.
n/a
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator), Primary Purpose: Treatment
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