Outcome
Type |
Measure |
Description |
Time frame |
Safety issue |
Primary |
Wisconsin Card Sorting Test (WCST) |
Wisconsin Card Sorting Test (WCST) is a neuropsychological measure of executive functioning, will be examined separately as well as in a composite with the other neuropsychological measures of executive functioning, range: -22 to 15, higher scores mean a worse outcome |
change from baseline to completion of computerized cognitive training (6 weeks) |
|
Primary |
Paced Auditory Serial Addition Test (PASAT) |
Paced Auditory Serial Addition Test (PASAT) is a neuropsychological measure of executive functioning, will be examined separately as well as in a composite with the other neuropsychological measures of executive functioning, range: -22 to 47, higher scores mean a better outcome |
change from baseline to completion of computerized cognitive training (6 weeks) |
|
Primary |
Delis Kaplan Executive Function System (D-KEFS) |
Delis Kaplan Executive Function System (D-KEFS) is a neuropsychological measure of executive functioning, will be examined separately as well as in a composite with the other neuropsychological measures of executive functioning, range: -39 to 27, higher scores mean a worse outcome |
change from baseline to completion of computerized cognitive training (6 weeks) |
|
Primary |
Behavior Rating Inventory of Executive Function (BRIEF) |
Behavior Rating Inventory of Executive Function (BRIEF) is a self-report measure of executive functioning, items are summed to create a total score, range: -32 to 30, higher scores mean a worse outcome |
change in subjective executive functioning from baseline to completion of computerized cognitive training (6 weeks) |
|
Primary |
WAIS-IV Digit Span Sequencing Subtest |
Wechsler Adult Intelligence Scale, Fourth Edition (WAIS-IV) Digit Span Sequencing subtest is a neuropsychological measure of executive functioning, will be examined separately as well as in a composite with the other neuropsychological measures of executive functioning, range: -3 to 3, higher scores mean a better outcome |
change from baseline to completion of computerized cognitive training (6 weeks) |
|
Primary |
N-Back Task Performance |
N-Back is a task that tests executive functioning, range: -.25 to .28, higher scores means a better outcome |
change from baseline to completion of computerized cognitive training (6 weeks) |
|
Primary |
Go/No-Go Task Performance |
Go/No-Go is a task that tests executive functioning, range: -.04 to .02, higher scores mean a worse outcome |
change from baseline to completion of computerized cognitive training (6 weeks) |
|
Secondary |
Clinician-Administered PTSD Scale for DSM 5 (CAPS-5) |
Clinician-Administered PTSD Scale for DSM 5 (CAPS-5) is a clinical interview assessing PTSD symptoms that will be administered at 3 time points: baseline, after completion of cognitive training, and after completion of Cognitive Processing Therapy, range: -38 to 18, higher scores mean a worse outcome |
change in PTSD symptoms from baseline to completion of Cognitive Processing Therapy (12 sessions completed after cognitive training), approximately 12 weeks after baseline assessment |
|
Secondary |
PTSD Checklist for DSM-5 (PCL-5) |
PTSD Checklist for DSM-5 (PCL-5) is a self-report questionnaire that will be administered at 15 time points: at baseline, after completion of cognitive training, at each of the 12 therapy sessions, and after completion of Cognitive Processing Therapy, range: -49 to 28, higher scores mean a worse outcome |
change in PTSD symptoms from baseline to completion of Cognitive Processing Therapy (12 sessions completed after cognitive training), approximately 12 weeks after baseline assessment |
|
Secondary |
World Health Organization Quality of Life - BREF |
World Health Organization Quality of Life - BREF (WHOQOL-BREF) is a self-report questionnaire assessing quality of life that will be administered at 3 time points: baseline, after completion of cognitive training, and after completion of Cognitive Processing Therapy. Four subscales are computed (range 4-20): physical health, psychological, social relationships, and environment, range: -2.7 to 6.7, higher scores mean a better outcome |
change in quality of life from baseline to completion of Cognitive Processing Therapy (12 sessions completed after cognitive training), approximately 12 weeks after baseline assessment |
|
Secondary |
Time (in Minutes) Spent Completing Cognitive Processing Therapy Homework |
At each of the CPT sessions, participants will report how much time they spent completing homework since the previous session |
time (in minutes) spent completing homework from CPT session 1 to CPT session 12 (across approximately 6 weeks, weeks 7-12 after baseline) |
|
Secondary |
Number of CPT Sessions Completed |
Number of CPT sessions completed out of a possible total of 12 sessions |
CPT sessions completed (out of a possible 12) after completing the cognitive training (across approximately 6 weeks, weeks 7-12 after baseline) |
|