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Postthrombotic Syndrome clinical trials

View clinical trials related to Postthrombotic Syndrome.

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NCT ID: NCT04411316 Withdrawn - Clinical trials for Deep Venous Thrombosis

Catheter-directed Thrombolysis Compared to Anticoagulation Alone for Acute Primary Iliofemoral Deep Venous Thrombosis

Start date: December 19, 2019
Phase: Phase 4
Study type: Interventional

Post-thrombotic syndrome (PTS) is a complication that can develop after deep vein thrombosis (DVT) of the lower extremities. PTS can occur at various times after the initial episode, but usually manifests within two years of initial DVT onset. Early and more complete thrombus clearance is believed by many to relieve venous outflow obstruction, preserve valvular function and reduce venous hypertension. Two previously published randomized controlled trials, the CAVENT trial and the ATTRACT trial, were larger and designed to investigate the efficacy of CDT. However, both of these trials included patients with iliofemoral as well as femoro-popliteal deep vein thrombosis. Our study will be limited to patients with iliofemoral deep vein thrombosis to assess whether Pharmacomechanical catheter-directed thrombolysis (PCDT) therapy utilizing AngioJet and tPA can safely and effectively reduce post thrombotic syndrome after 24 months.

NCT ID: NCT03039517 Withdrawn - Clinical trials for Deep Vein Thrombosis

Post Thrombotic Syndrome Prevention Study

Start date: January 2017
Phase: N/A
Study type: Interventional

This is a two arm, prospective, single center, randomized clinical trial. Subjects will be randomly assigned into one of two groups using block randomization technique in a 1:1 ratio. The control group will receive care using elastic compression stocking and the intervention group will use the ACTitouch device. Stratified randomization will occur based on whether the Deep Vein Thrombosis (DVT) has iliac or non-iliac involvement. Subjects will be followed for 2 years with clinic visits occurring at 1, 3, 6, 12, and 24 months.

NCT ID: NCT02767232 Withdrawn - Clinical trials for Deep Vein Thrombosis

Pediatric High-Risk Deep Venous Thrombosis Lytic Outcomes Trial

PHLO
Start date: July 2018
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine if the use of adjunctive catheter-directed thrombolysis (CDT), which includes the intrathrombus administration of rt-PA (Activase/Alteplase), can prevent post-thrombotic syndrome (PTS) in pediatric patients with symptomatic proximal deep vein thrombosis (DVT) as compared with optimal standard anticoagulation alone.

NCT ID: NCT01615692 Withdrawn - Clinical trials for Deep Vein Thrombosis

The 36-month Extension to Follow up Sub Study

Start date: June 2004
Phase:
Study type: Observational

The purpose of this study is to evaluate leg health for one additional year in patients with symptomatic proximal deep venous thrombosis who did not already develop Post-Thrombotic Syndrome (PTS) during the 2 years of follow up in the SOX Trial.