Tranexamic Acid for the Prevention of Postpartum Haemorrhage

Status Recruiting

Clinical Trial Summary

Use of tranexamic acid (TXA) for the prevention of postpartum haemorrhage (PPH) after cesarean section in high-risk patients ( a randomized control trial ).

Clinical Trial Description

Participants will be divided into two groups: a study group & a control group. In addition to the standard management, the study group will be given TXA 1 gm (100 mg/ml) slowly intravenous infusion during delivery after clamping of the cord (administered over 10 minutes at 1 ml/minute). The second dose of TXA 1 g Intravenous can be given if: - Bleeding continues after 30 minutes - Bleeding restarts within 24 hours of completing the first dose While the control group will not be given TXA and we will compare the results in both groups (amount of blood loss during operation to assess efficacy of TXA in prevention of PPH and reduction of intra and postoperative blood loss and to assess its safety and benefit in the reduction of incidence of hysterectomy or blood transfusion requirements). ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04707950
Study type	Interventional
Source	Benha University
Contact	Ahmed A Morad, MD
Phone	0201224214435
Email	awalid217@yahoo.com
Status	Recruiting
Phase	Phase 1/Phase 2
Start date	January 1, 2020
Completion date	March 30, 2021

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